A 33-year-old woman underwent bilateral LASIK in May 2001 for high myopia.Preoperative evaluation revealed clear corneas with no evidence of anteriorbasement membrane dystrophy. The procedure was uneventful in the right eye.In the left eye, however, a 2.0 × 2.0-mm corneal epithelial defect wasnoted in the superior paracentral location after creation of the flap, andthe epithelium surrounding the defect was noted to be generally poorly adherentto the Bowman layer. A bandage soft contact lens was placed on the left eye,and the patient was instructed to use a combination of 0.1% fluorometholoneand 0.3% ofloxacin eyedrops, 4 times daily, in both eyes. On the first postoperativeday, the patient's uncorrected visual acuity (UCVA) was 20/70 OS. On ophthalmicexamination, the contact lens was in place, and there was mild flap edema,but no epithelial defect or lamellar keratitis was noted. The soft contactlens was removed, and on the next day, the patient manifested acutely withreports of decreased vision, foreign body sensation, photophobia, tearing,and pain in the left eye. Visual acuity was still 20/70 OS, but a recurrent2.0 × 1.9-mm epithelial defect was found in the same location as whenthe defect had first been noted. No lamellar keratitis was found, and a bandagesoft contact lens was placed on the eye. On the third postoperative day, thepatient's visual acuity was decreased to 20/400 OS, and moderately severeDLK was found. Treatment with 1% prednisolone acetate was instituted everyhour around the clock in place of the 0.1% fluorometholone. By 2 days later,the DLK began to recede, and the epithelial defect was healed. Eight monthspostoperatively, the patient's best-spectacle-corrected visual acuity (BSCVA)was 20/20 OS.