Case 1. An infant girl was born at 24 weekspostconceptual age and weighed 750 g. The postnatal course was complicatedby bronchopulmonary dysplasia, apnea, patent ductus arteriosis, anemia, hypertension,gastrointestinal reflux, and subclinical necrotizing enterocolitis. The patientalso developed candidemia with blood and urine cultures positive for organismsat 3 weeks of age. She was found to have a large right atrial mass compatiblewith fungus that showed evidence of inferior vena cava obstruction. She wastreated with amphotericin B and fluconazole for a total of 3 months. All cultureswere negative for organisms for the final 2 weeks of her treatment prior todischarge from the neonatal intensive care unit. Serial ocular examinationsrevealed intralenticular opacities and a persistent tunica vasculosa lentisin the right eye by 3 weeks of age, which resolved itself by age 5 weeks.The left eye was not involved. At 3 months of age she was noted to have achorioretinal scar in the right eye. At age 4 months, her mother observeda "white spot" at the edge of her pupil.