0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Clinical Trials |

A Randomized Trial of the Effects of Rigid Contact Lenses on MyopiaProgression

Jeffrey J. Walline, OD, PhD; Lisa A. Jones, PhD; Donald O. Mutti, OD, PhD; Karla Zadnik, OD, PhD
Arch Ophthalmol. 2004;122(12):1760-1766. doi:10.1001/archopht.122.12.1760.
Text Size: A A A
Published online

Objective  To compare the effects of rigid gas-permeable contact lenses (RGPs)and soft contact lenses (SCLs) on myopia progression in children.

Methods  We randomly assigned 116 subjects to wear RGPs or SCLs. Subjects underwentcycloplegic autorefraction, keratometry, and A-scan ultrasonographic axiallength measurements at each annual visit. All analyses were conducted accordingto the original randomization assignment. The primary outcome measure wasthe 3-year change in spherical equivalent cycloplegic autorefraction.

Results  The mean ± SD spherical equivalent cycloplegic refractiveerror progressed –1.56 ± 0.95 diopters (D) for RGPwearers and –2.19 ± 0.89 D for the SCL wearers duringthe 3 years of the study (analysis of covariance [ANCOVA], P<.001). The axial growth of the eyes was not significantly differentbetween treatment groups (ANCOVA, P = .57).The steep corneal meridian of the RGP wearers steepened 0.62 ± 0.60D, and that of the SCL wearers steepened 0.88 ± 0.57 D duringthe 3 years (ANCOVA, P = .01).

Conclusions  The RGP wearers’ myopia progressed less than that of the SCL wearers.The corneal curvature of the SCL wearers steepened more than that of the RGPwearers, but the axial growth was not significantly different between thegroups. Most refractive error treatment effect was limited to the first yearof the trial. The results of the study provide information for eye care practitionersto share with their patients, but they do not indicate that RGPs should beprescribed primarily for myopia control.

Figures in this Article

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Place holder to copy figure label and caption
Figure 1.

Flow diagram of subjects in the ContactLens and Myopia Progression Study. RGPs indicates rigid gas-permeable contactlens; SCLs, soft contact lenses.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

A, Mean ± SD cycloplegicspherical equivalent refractive error for wearers of rigid gas-permeable contactlenses (RGPs) and soft contact lenses (SCLs). The shaded portion representsthe run-in period, when all subjects wore RGPs. The asterisks indicate a significantdifference in refractive error between treatment groups (P<.05). B, Mean ± SD curvature of the steepcorneal meridian for RGP and SCL wearers from the initial visit to the endof the study. The shaded portion represents the run-in period, when all subjectswore RGPs. The asterisks indicate a significant difference in corneal curvaturebetween treatment groups (P<.05). The dashedline indicates the initial curvature of the steep corneal meridian. Cornealflattening is seen during the run-in period, with a return to the initialcorneal curvature for the RGP wearers, and the additional steepening in theSCL wearers. C, Mean ± SD axial length for RGP and SCL wearersfrom the initial visit to the end of the study. Axial lengths were not measuredat the initial visit, so no axial length data were available before randomization.There were no significant differences between the treatment groups at anyof the visits (P<.05).

Graphic Jump Location

Tables

References

Correspondence

CME


You need to register in order to view this quiz.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
Jobs
brightcove.createExperiences();