Dr Johnson's passion was to understand the morphological architecture of the eye, particularly the trabecular meshwork. Whether a light micrograph or a transmission or scanning electron micrograph, he believed that the images taught us something about the function of the trabecular meshwork. Throughout his career he described similarities and differences between normal trabecular meshworks and meshworks found in primary open-angle glaucoma, pseudoexfoliation glaucoma, and pigmentary and steroid-induced glaucoma. He, along with Elke Lutjen-Drecoll, MD, of Germany, showed that the thickened tendons and sheaths within the trabecular meshwork that are hallmark ultrastructural changes in glaucoma do not cause the elevation of intraocular pressure but represent a marker of an underlying pathological process. His most recent pursuit was to describe the ultrastructural changes that follow nonpenetrating laser trabeculoplasty, where regions between laser scars appear “foamy or expanded.” It was Dr Johnson's belief that these expanded regions were areas of extracellular remodeling that helped improve fluid flow through the trabecular meshwork. He recently found similar regions located under collector channels in normal eyes, suggesting to him that the expanded juxtacanalicular regions may be the main trabecular meshwork flow areas. At the time of his death, he was characterizing these expanded juxtacanalicular regions in glaucomatous eyes, where he believed he would find pathophysiologic differences between normal and glaucomatous trabecular meshworks.