After 4 months of quiescence, the disease again reactivated with new infiltrates and melts resulting in a flat chamber in the right eye and new guttering in the periphery of the left corneoscleral graft (Figure, C and D). Cyclophosphamide treatment at a dosage of 100 mg/d was commenced with another course of oral prednisolone, and mycophenolate treatment was stopped. Three weeks later, the patient developed microscopic hematuria and bloody stools, so cyclophosphamide treatment had to be discontinued. Stool cultures were negative for parasites. The infiltrates and melts in the right eye continued to be active, so infliximab at a dosage of 5 mg/kg was added, combined with oral cyclosporine. The inflammation in both eyes responded rapidly to this treatment, with gradual return of the inflammation in the 2-week interval between infusions. The patient received 3 infusions over 6 weeks. A right conjunctival recession and cautery procedure was carried out after another perforation, which sealed spontaneously under a bandage lens, and mycophenolate was again added to the immunosuppressive regimen.