A 73-year-old man underwent cataract extraction via phacoemulsification with a temporal clear corneal incision. He had a history of tamsulosin hydrochloride (Flomax) use, and iris hooks were placed to manage intraoperative floppy iris syndrome. On postoperative day 1, visual acuity was 20/40; however, within 24 hours, visual acuity decreased to 20/400 and substantial corneal edema had developed. There were no signs of intraocular infection, and combined treatment with prednisolone acetate, 1%, and a sodium chloride solution, 5%, was started. The patient's condition did not improve during the next 2 weeks, and he was referred to our institution for evaluation of possible pseudophakic bullous keratopathy. Visual acuity was still 20/400, without an afferent pupillary defect. Intraocular pressure was normal. Slitlamp examination revealed quiet conjunctiva and diffuse corneal edema with a quiltlike pattern of deep stromal folds (Figure, A). Through the hazy view, there was the suggestion of a large DMD. The remainder of the ophthalmologic examination yielded unremarkable findings. The patient underwent both UBM (Figure, B) and anterior segment OCT (Figure, C), which confirmed a large, planar, nonscrolled DMD involving almost the entire cornea. After an initial intracameral injection of sulfur hexafluoride, 20%, failed to enable reattachment of the DM, a second, larger injection of sulfur hexafluoride, 20%, was administered. One month postoperatively, there was complete resolution of the DMD (Figure, D) and visual acuity was 20/30.