Postoperative care included 1% atropine sulfate once daily and a combination of tobramycin sulfate and dexamethasone ointment (Tobradex) twice daily for 1 week. General health, presence of conjunctival hyperemia, subconjunctival hemorrhage, biomaterial extrusion, suture exposure, discharge, infection, corneal edema, corneal epithelial defects, anterior chamber reaction, quality of red reflex, and any complications were assessed and recorded at each postoperative examination on days 1, 3, 7, 14, and 21. Slitlamp biomicroscopy was performed on postoperative days 3, 7, and 21. Conjunctival hyperemia was rated by intensity and location in each of the eyes. The examination and grading of the conjunctival hyperemia was performed by one of us (R.S.A.) unaware of the biomaterial. The grading was performed as follows: grade 0 indicated no hyperemia; grade 1, mild hyperemia; grade 2, moderate hyperemia; and grade 3, severe hyperemia. The animals were killed at the end of 3 weeks (sedation with a large dose of ketamine followed by a lethal dose of intracardiac, intravenous pentobarbital sodium [100 mg/kg]). The eyes were enucleated, with care taken not to disturb the conjunctiva in the quadrant containing the implant.