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Research Letters |

Anterior Segment Optical Coherence Tomography as a Diagnostic Tool for Cyclodialysis Clefts FREE

Aránzazu Mateo-Montoya, MD; Sylvain Dreifuss, MD
Arch Ophthalmol. 2009;127(1):109-116. doi:10.1001/archophthalmol.2008.561.
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Published online

Anterior segment optical coherence tomography (OCT) is a noninvasive, painless, noncontact technique that provides accurate and reproducible images. This technique correlates well with ultrasound biomicroscopy, allows observation of iridocorneal angle abnormalities in the presence of opaque media, and is easier to perform than ultrasound biomicroscopy.

A cyclodialysis cleft results from separation of the longitudinal ciliary muscle fibers from the scleral spur and establishes a new drainage pathway for aqueous humor between the anterior chamber and the suprachoroidal space. This new drainage channel increases uveoscleral outflow and may result in chronic ocular hypotonia; it is sometimes complicated by decreased visual acuity, a shallow anterior chamber, ciliochoroidal effusion, optic disc edema, retinal folds, hypotonus maculopathy, and engorgement and stasis of retinal veins.1

Slitlamp examination using a gonioscope has been the most common method used to confirm the existence of clefts. However, it cannot be used in patients with hyphema, corneal opacity, and excessive hypotonia after trauma or surgery. In these patients, ultrasound biomicroscopy (UBM) has been a useful tool for visualizing the anterior eye segment.25 We demonstrate the use of OCT as a new technique that provides anterior segment imaging and allows identification of cyclodialysis clefts in correlation with clinical examination and UBM.

A 38-year-old man was initially seen after having been hit in the left eye with a heavy bungee cord. He noted severe pain and blurred vision. Distance visual acuity was 20/20 OD and 20/80 OS. The right eye was unremarkable. Eyelid ecchymosis was seen in the left eye, and anterior segment examination revealed diffuse conjunctival hyperemia, Descemet folds, grade 1 hyphema (less than one-third of the anterior chamber), iritis, and an atonic pupil. The lens was clear, and there was no evidence of phacodonesis. Applanation intraocular pressure (IOP) was 14 mm Hg in each eye. Funduscopy revealed a healthy optic disc, macula, and peripheral retina in each eye.

The patient was treated with topical prednisolone acetate, 1%; scopolamine hydrobromide; and bed rest with elevation of the head of the bed 30° to 45°. He was examined daily. After a week, visual acuity was 20/120 OS. There was resolution of the hyphema, persistent mild iritis, a shallow anterior chamber, and atrophy of the inferior iris. His left eye IOP was 5 mm Hg. Ophthalmoscopy revealed optic disc edema, radiating retina folds around the macula, and mild vascular tortuosity. Gonioscopy revealed a cyclodialysis cleft at the 7- to 8-o’clock position (Figure 1). A diagnosis of hypotonus maculopathy secondary to a posttraumatic cyclodialysis cleft was made.

Place holder to copy figure label and caption
Figure 1.

A cyclodialysis cleft (arrow) revealed by gonioscopy.

Graphic Jump Location

Both UBM (Figure 2) and anterior segment OCT (Figure 3) demonstrated the cyclodialysis cleft at the 7- to 8-o’clock position. Anterior segment OCT also provided high-resolution images that identified the disinsertion of the ciliary body from the scleral spur and an associated ciliary body detachment, confirming the diagnosis (Figure 3).

Place holder to copy figure label and caption
Figure 2.

A cyclodialysis cleft (arrow) revealed by ultrasound biomicroscopy.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 3.

A cyclodialysis cleft (arrows) confirmed by anterior segment optical coherence tomography. Disinsertion of the ciliary body from the scleral spur and an associated ciliary body detachment were also revealed.

Graphic Jump Location

Since the iritis was almost completely resolved and there is some literature that suggests that corticosteroid therapy should be limited in patients with cyclodialysis6 because of the possibility of a secondary increased IOP and inhibition of scar formation, administration of prednisolone acetate was stopped and only scopolamine hydrobromide therapy was continued. Six months later, distance visual acuity was 20/20 OS and near visual acuity was 20/20 with a correction of +3 diopters in that eye. This result suggested that the patient had lost his accommodation, probably because of the ciliary body detachment. The IOP in the left eye was 10 mm Hg, and macular folds were less marked. Repeated UBM and anterior segment OCT showed persistence of the cyclodialysis cleft and an even larger ciliary body detachment.

The patient's vision status was excellent compared with that of other patients with cyclodialysis clefts described in the literature.7 Because visual acuity was good and IOP was normal, continued follow-up was agreed on. However, the patient was informed of the risk of continued enlargement of the cyclodialysis cleft; if this were to happen, different treatment options would be proposed, such as suturing the ciliary body to the sclera, vitrectomy with pars plana cryopexy for the detached ciliary body, and gas tamponade8 or argon laser photocoagulation.9

Cyclodialysis clefts occur most commonly after trauma and sometimes after surgery. Intentional surgical cyclodialysis has been used for the treatment of glaucoma.26 Gonioscopy has been the classic method for visualizing a cyclodialysis cleft; however, cyclodialysis clefts could be missed in traumatized eyes with hazy media, distorted anatomy, or hypotonia. In these cases, UBM has been useful.25

We presented diagnostic images of a cyclodialysis cleft using a new technique, anterior segment OCT. This technique provided high-resolution images of the cyclodialysis cleft, showing its exact location and the extent of the disinsertion of the ciliary body from the scleral spur and an associated ciliary body detachment. These images served to confirm the clinical diagnosis.

Anterior segment OCT is a noninvasive tool that provides accurate and reproducible images of the anterior segment. This technique has good correlation with UBM and allows observation of iridocorneal angle abnormalities in the presence of turbid media, hypotonia, and abnormal anterior segment anatomy. In addition, anterior segment OCT has some advantages compared with UBM: it does not require any contact with the patient's eye, it does not require the use of topical gel, it is more comfortable for the patient, it is easier to perform, and it does not risk traumatizing or contaminating the cornea.

Correspondence: Dr Mateo-Montoya, Ophthalmology Clinic, Department of Clinical Neurosciences, Geneva University Hospital, 22 rue Alcide-Jentzer, CH-1211 Geneva 14, Switzerland (arancha.mateo@gmail.com).

Submitted for Publication: June 1, 2008; final revision received August 19, 2008; accepted August 25, 2008.

Financial Disclosure: None.

Aminlari  ACallahan  CE Medical, laser, and surgical management of inadvertent cylodialysis cleft with hypotony. Arch Ophthalmol 2004;122 (3) 399- 404
PubMed Link to Article
Gentile  RCPavlin  CJLiebmann  JM  et al.  Diagnosis of traumatic cyclodialysis by ultrasound biomicroscopy. Ophthalmic Surg Lasers 1996;27 (2) 97- 105
PubMed
Kaushik  SArya  SKKochhar  S Cyclodialysis cleft diagnosed by conventional ultrasonography. Ophthalmic Surg Lasers 2000;31 (4) 346- 349
PubMed
Park  MKondo  T Ultrasound biomicroscopic findings in a case of cyclodialysis. Ophthalmologica 1998;212 (3) 194- 197
PubMed Link to Article
González Martíin-Moro  JMuñoz-Negrete  FJRebolleda  GLara Medina  JGarcíia-Feijoó  J Ultrasonic biomicroscopic findings after spontaneous resolution of a traumatic cyclodialysis [in Spanish]. Arch Soc Esp Oftalmol 2003;78 (4) 211- 214
PubMed Link to Article
Brandonisio  TMNewman  TL Hypotonous maculopathy and normal visual acuity secondary to post-traumatic cyclodialysis cleft. Optometry 2002;73 (10) 620- 625
PubMed
Chaudhry  NAFlynn  HW  JrPalmberg  PF Elastic cord-induced cyclodialysis cleft and hypotony maculopathy. Ophthalmic Surg Lasers 1999;30 (8) 678- 680
PubMed
Takaya  KSuzuki  YNakazawa  M Four cases of hypotony maculopathy caused by traumatic cyclodialysis and treated by vitrectomy, cryotherapy, and gas tamponade. Graefes Arch Clin Exp Ophthalmol 2006;244 (7) 855- 858
PubMed Link to Article
Joondeph  HC Management of postoperative and post-traumatic cyclodialysis clefts with argon laser photocoagulation. Ophthalmic Surg 1980;11 (3) 186- 188
PubMed

Figures

Place holder to copy figure label and caption
Figure 1.

A cyclodialysis cleft (arrow) revealed by gonioscopy.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

A cyclodialysis cleft (arrow) revealed by ultrasound biomicroscopy.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 3.

A cyclodialysis cleft (arrows) confirmed by anterior segment optical coherence tomography. Disinsertion of the ciliary body from the scleral spur and an associated ciliary body detachment were also revealed.

Graphic Jump Location

Tables

References

Aminlari  ACallahan  CE Medical, laser, and surgical management of inadvertent cylodialysis cleft with hypotony. Arch Ophthalmol 2004;122 (3) 399- 404
PubMed Link to Article
Gentile  RCPavlin  CJLiebmann  JM  et al.  Diagnosis of traumatic cyclodialysis by ultrasound biomicroscopy. Ophthalmic Surg Lasers 1996;27 (2) 97- 105
PubMed
Kaushik  SArya  SKKochhar  S Cyclodialysis cleft diagnosed by conventional ultrasonography. Ophthalmic Surg Lasers 2000;31 (4) 346- 349
PubMed
Park  MKondo  T Ultrasound biomicroscopic findings in a case of cyclodialysis. Ophthalmologica 1998;212 (3) 194- 197
PubMed Link to Article
González Martíin-Moro  JMuñoz-Negrete  FJRebolleda  GLara Medina  JGarcíia-Feijoó  J Ultrasonic biomicroscopic findings after spontaneous resolution of a traumatic cyclodialysis [in Spanish]. Arch Soc Esp Oftalmol 2003;78 (4) 211- 214
PubMed Link to Article
Brandonisio  TMNewman  TL Hypotonous maculopathy and normal visual acuity secondary to post-traumatic cyclodialysis cleft. Optometry 2002;73 (10) 620- 625
PubMed
Chaudhry  NAFlynn  HW  JrPalmberg  PF Elastic cord-induced cyclodialysis cleft and hypotony maculopathy. Ophthalmic Surg Lasers 1999;30 (8) 678- 680
PubMed
Takaya  KSuzuki  YNakazawa  M Four cases of hypotony maculopathy caused by traumatic cyclodialysis and treated by vitrectomy, cryotherapy, and gas tamponade. Graefes Arch Clin Exp Ophthalmol 2006;244 (7) 855- 858
PubMed Link to Article
Joondeph  HC Management of postoperative and post-traumatic cyclodialysis clefts with argon laser photocoagulation. Ophthalmic Surg 1980;11 (3) 186- 188
PubMed

Correspondence

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