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Special Article |

The Evolution of Retinal Surgery A Personal Story FREE

Harvey Lincoff, MD
[+] Author Affiliations

Author Affiliations: The New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York.


Arch Ophthalmol. 2009;127(7):923-928. doi:10.1001/archophthalmol.2009.164.
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Published online

I would like to thank The Retinal Research Foundation, The Schepens International Society, and Alice McPherson for establishing this lecture to honor Charles Schepens and for inviting me to be the first lecturer.

I met Charles Schepens (Figure 1) in 1955 when I was sent to the Howe Laboratory in Boston for a Heed fellowship with David Cogan. Dr Schepens had emigrated to the United States and to the Howe Laboratory from London 8 years before. Just before I left for Boston, Edward Norton, a friend at the New York Hospital, advised me to look in on Dr Schepens while in Boston. Charles Schepens' reputation for treating and curing retinal detachments had reached New York, and there was disbelief. A leading retinal surgeon in New York—there were 2—referred to him as Boston Charlie, a takeoff on Boston Blackie, a fictional gangster in the movies. Retinal detachment was a neglected disorder at Bellevue Hospital where I trained, as well as elsewhere in the United States. At Bellevue it was assigned to a junior resident for repair. We knew there was supposed to be a retinal break, but as the breaks tended to be in the periphery and we only used direct ophthalmoscopy, we rarely found them. The routine was prolonged bed rest with binocular occlusion and then the application of perforating diathermy to the posterior edge of the detachment and drainage of subretinal fluid, followed by more binocular occlusion and bed rest. Twenty-five days in the hospital for a retinal detachment was not uncommon.

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Figure 1.

Photograph of Charles Schepens, 1955.

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In Boston, when I wasn't working with Dr Cogan in the Howe Laboratory, I would slip downstairs to the retinal clinic to watch Drs Schepens, Okamura, and Brockhurst, using indirect ophthalmoscopy through a binocular scope (Figure 2) that Drs Schepens and Pomerantzev had developed, draw the fundus and retinal detachment to the ora serrata and find the retinal breaks.1,2 The drawings were in a color code (Figure 3): red for attached retina and arteries, blue for detached retina and veins, green for opacities in the media, and yellow for exudate. The scallop at the border indicated that you had seen the ora seratta; if a segment was missing, you looked for it at the operating table with more scleral depression. Retinal detachment was operated upon under general anesthesia. The drawings were taken to the operating room and hung adjacent to the table for reference of the meridian and anterior posterior position of the retinal break.

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Figure 2.

Schepens binocular ophthalmoscope.

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Figure 3.

Retinal drawing in color code.

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I can remember standing behind Dr Schepens at the operating table and peering over his shoulder as he localized and marked the posterior edge of a break. Then he made a lamellar dissection centered on the mark, applied multiple rows of diathermy posterior to the break, and inserted a section of polyethylene tube to create a buckle to augment the diathermy barrier that was intended to prevent a leak from the retinal break detaching the posterior retina (Figure 4).3 It succeeded in most eyes with small breaks that were supported by the buckle (Figure 5A). In the presence of a larger break, however, the anterior end of the break would leak anteriorly and redetach the retina (Figure 5B). To counter this, Dr Schepens extended the buckle to 180° and made several radial lines of coagulation to the ora (Figure 6A). Still, in a number of eyes the anterior leak would circumvent the extent of the buckle (Figure 6B). The solution was a 360° buckle; the encircling buckle was a pragmatic solution to the anterior leak (Figure 7).4 Eventually, it became apparent that we should buckle the anterior end of the break as well as the posterior end, and for this purpose numerous silicone forms (Figure 8) were developed to buckle completely breaks of all sizes and shapes. Encirclement was no longer needed, but it was so embedded in our technique that it was retained. Dr Schepens maintained that it served to counter future vitreous traction. It also preserved the barrier concept for any undiscovered breaks in the periphery. To this day, it remains a common addition to most procedures for retinal detachment.

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Figure 4.

Scleral buckle with diathermy and polyethylene tube.

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Figure 5.

Quadrant buckle (A) leaking anteriorly (B).

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Figure 6.

The 180° buckle (A) leaking anteriorly and inferiorly (B).

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Figure 7.

Encircling buckle confining an anterior leak (A) and augmented by a local buckle (B).

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Figure 8.

Numerous silicone forms of various size and shapes.

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I returned to Bellevue with a binocular indirect scope—it was 1 of 3 in New York—and I taught the residents to use it. Dr Devoe, an erudite chairman and cataract surgeon, viewed our drawings to the ora with skepticism. I went back to Boston periodically in the first years to confer with the expanding retina group, which added Regan and McMeel, and then Freeman, Pruett, Tolentino, Hirose, and Trempe. The Schepens Retina Associates and the Eye Research Institute acquired a national reputation for excellence in attaching the retina.

In 1957 I moved to The New York Hospital to fill Norton's place when he moved to Florida. Under Norton the Retina Service at the New York Hospital had been expanding; this was abruptly brought to my attention when a senior cataract surgeon complained to administration that the Retinal Service was preempting too many beds. Cataract surgery in the ‘50s was an inpatient procedure. In response we reduced preoperative binocular occlusion and bed rest to 1 day and postoperative occlusion to 3 days. More recently, with recognition of the positive effect of ambulatory binocular occlusion, we reduce bed occupancy and meet Medicare and the insurance industry's requirement by admitting on the day of surgery after 1 or 2 days of ambulatory binocular occlusion at the patient's home.5 The patient can peek momentarily from the unaffected eye for toilet and to get in and out of the car on his return to the office. Ambulatory occlusion induces regression of a detachment and will promote settling of acute vitreous hemorrhage. The critical factor appears to be the cessation of gaze movement. Body or head position do not seem to matter.

In 1958 I was sent to Bonn, Germany, to evaluate the photocoagulator that Meyer-Schwickerath had developed.6 As I was leaving, Edward Norton asked me to look in on “this fellow Custodis,” who had said at one of the first Retina Society meetings at Ipswich [Massachusetts] the previous year that he does not drain subretinal fluid.7 In Bonn I made a positive assessment of the photocoagulator, and after a week I took a train 60 km north to Duesseldorf and arrived in time to see Ernst Custodis, using monocular indirect ophthalmoscopy, localize a retinal break in a bullous retinal detachment, sew a large red rubbery explant (polyviol) over the break with a single mattress suture, and not drain subretinal fluid. The operation took less than an hour; our operation with scleral dissection and encirclement took 2 to 3 hours. I examined Custodis' patient the next morning and found the retina attached. Not only was the retina attached but the vitreous crystal clear. After a scleral resection, silicone implant, encirclement, and drainage, we were accustomed to a cloudy vitreous for a number of days. I stayed in Duesseldorf for a week to watch Custodis, to make sure I had not witnessed a fluke, then flew back to New York with a pocket full of polyviol explants, began doing the procedure with equal results, and wrote about it in the Archives.8 Before long I was invited to share a platform with Dr Schepens to describe the nondrainage procedure. Dr Schepens’ comment was, “Not draining subretinal fluid is all right for New York doctors because New York doctors never sleep.”

The polyviol explant operation was short-lived. In the next year Dr Schepens and the Retina Associates published a report of 25 operations using polyviol and described 7 infections, 4 of which were scleral abscesses and 1 of which perforated and required evisceration. The publication precluded further use of polyviol in the United States. Unwilling to give up the procedure, I consulted with Dow Corning about making an explant with the elastic properties of polyviol, and they came up with silicone sponge.9 At a subsequent meeting, Dr Schepens acknowledged the silicone sponge and said, “It is like a New York apartment house where every room is filled with staphylococci that are multiplying like mad.”

I asked Dow Corning about making a closed-cell sponge and they did, and the sponge operation survived. In the first 40 sponge operations, however, I encountered a scleral abscess that recovered without serious consequence after removal of the sponge. We made a rabbit model of scleral abscess, and by elimination we learned that diathermy necrosis of the sclera was the critical component.10 If we eliminated diathermy, abscess did not occur. We searched for an alternative to perforating diathermy. Surface diathermy caused superficial scleral necrosis. Then on a visit to my dermatologist I saw him applying a carbon dioxide pencil to an indolent skin lesion. He said he did it to incite an inflammatory response. I took a pencil to the laboratory, applied it to a rabbit eye, and observed a white lesion in the retina in response. Over the next week the lesion evolved with pigmentation, much like a diathermy lesion. On subsequent dissection, the retina appeared adherent, and microscopy revealed the sclera undamaged. We began using cryo applications made with a liquid nitrogen probe that John McLean developed, on patients with retinal detachments, and in 1963 reported on the first 30 patients to the American Academy.11

At a subsequent meeting with Dr Schepens, we were introduced as Drs Hot and Cold. Dr Schepens acknowledged the value of cryo for transconjunctival use, but questioned whether the adhesion was as strong as that produced by diathermy and whether the dispersion of pigment that excessive freezing might produce would prove to be prohibitory. That was an astute observation and led to more temperate applications of cryo. Medical Instruments Research Associates of Boston subsequently developed a carbon dioxide instrument that yielded a more moderate freeze.

My last encounter with Dr Schepens occurred at a Retina Society meeting a few years ago. It was after the sessions that day that Ingrid Kreissig and I appeared on a porch where dinner was being served. Dr Schepens and his wife were already seated at a table and Dr Schepens beckoned for us to join them, and we did. We talked about the meeting and the papers. I had drunk a glass of wine when I said to Dr Schepens, “I always hoped that one day you would ask me to join you and the Retina Associates in Boston.” Ingrid flushed with embarrassment, there was a perceptible pause, then Dr Schepens replied, “You should have told me.”

On a final note, one evening 40 years ago as I was about to sit down for dinner, Edward Norton called and said in a voice shaking with excitement, “We have just split the atom”; Robert Machemer had done the first pars plana vitrectomy.12

Vitrectomy has progressed to where it replaces scleral buckling for retinal detachment on some retinal services. Most vitrectomy procedures include an encircling band, presumably, as Dr Schepens said, to counteract future vitreous contraction and as a barrier for unperceived breaks in the periphery. More recently we have demonstrated that the encircling band diminishes the volume of the ocular pulse by 40%, and it is recommended that the band be cut after 6 months to restore volume.13

I want to thank Alice McPherson again for proposing this lecture to honor Charles Schepens, whose binocular ophthalmoscope and meticulous preoperative study and operative technique enabled us to find the breaks in the periphery of a retinal detachment to buckle them and attach the retina. As a result, blindness from retinal detachment that was frequent before the emergence of Jules Gonin in 1929 has become rare since the emergence of Charles Schepens in 1950.

ARTICLE INFORMATION

Correspondence: Harvey Lincoff, MD, The NY Presbyterian Hospital-Weill Cornell Medical Center, 1305 York Ave, Ste Y1114, New York, NY 10021 (mcaulfie@med.cornell.edu).

Submitted for Publication: December 4, 2008; final revision received December 4, 2008; accepted December 5, 2008.

Financial Disclosure: None reported.

Additional Contributions: We gratefully acknowledge the assistance of Dominik Uram, MD, and MarieElena Caulfield.

Schepens  CL A new ophthalmoscope demonstration. Trans Am Acad Ophthalmol Otolaryngol 1947;51298- 301
Schepens  CLBahn  GC Examination of the ora serrata: its importance in retinal detachment. AMA Arch Opthalmol 1950;44677- 690
Link to Article
Schepens  CLOkamura  IDBrockhurst  RJRegan  CD Scleral buckling procedures V: synthetic sutures and silicone implants. Arch Ophthalmol 1960;64868- 881
PubMed Link to Article
Schepens  CL Symposium: present status of retinal detachment surgery: scleral buckling with circling element. Trans Am Acad Ophthalmol Otolaryngol 1964;68959- 979
PubMed
Lincoff  HStopa  MKreissig  I Ambulatory binocular occlusion. Retina 2004;24 (2) 246- 253
PubMed Link to Article
Meyer-Schwickerath  G Lichtcoagulation: Buch. Augenarzt Klin Monatsbl Augenheilkd 1959;331- 96
Custodis  E Bedeutet die Plombenaufnahung auf die Sclera. Ber Deutsch Ophth Ges 1953;58102
Lincoff  HABaras  J McLean  J Modifications to the Custodis procedure for retinal detachment. Arch Ophthalmol 1965;73160- 163
PubMed Link to Article
Lincoff  H McLean  JM Modifications to the Custodis procedure II: a new silicone implant for large tears. Am J Ophthalmol 1967;64 (5) 877- 879
PubMed
Langston  RLincoff  HA McLean  JM Scleral abscess II: the experimental production in animals. Arch Ophthalmol 1965;74 (5) 665- 668
PubMed Link to Article
Lincoff  HA McLean  JM Cryosurgical treatment of retinal detachment II. Trans Am Acad Ophthalmol Otolaryngol 1966;70 (2) 202- 211
PubMed
Machemer  RNorton  EW A new concept for vitreous surgery 3: indications and results. Am J Ophthalmol 1972;74 (6) 1034- 1056
PubMed
Lincoff  HStopa  MKreissig  I  et al.  Cutting the encircling band. Retina 2006;26 (6) 650- 654
PubMed Link to Article

Figures

Place holder to copy figure label and caption
Figure 1.

Photograph of Charles Schepens, 1955.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

Schepens binocular ophthalmoscope.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 3.

Retinal drawing in color code.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 4.

Scleral buckle with diathermy and polyethylene tube.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 5.

Quadrant buckle (A) leaking anteriorly (B).

Graphic Jump Location
Place holder to copy figure label and caption
Figure 6.

The 180° buckle (A) leaking anteriorly and inferiorly (B).

Graphic Jump Location
Place holder to copy figure label and caption
Figure 7.

Encircling buckle confining an anterior leak (A) and augmented by a local buckle (B).

Graphic Jump Location
Place holder to copy figure label and caption
Figure 8.

Numerous silicone forms of various size and shapes.

Graphic Jump Location

Tables

References

Schepens  CL A new ophthalmoscope demonstration. Trans Am Acad Ophthalmol Otolaryngol 1947;51298- 301
Schepens  CLBahn  GC Examination of the ora serrata: its importance in retinal detachment. AMA Arch Opthalmol 1950;44677- 690
Link to Article
Schepens  CLOkamura  IDBrockhurst  RJRegan  CD Scleral buckling procedures V: synthetic sutures and silicone implants. Arch Ophthalmol 1960;64868- 881
PubMed Link to Article
Schepens  CL Symposium: present status of retinal detachment surgery: scleral buckling with circling element. Trans Am Acad Ophthalmol Otolaryngol 1964;68959- 979
PubMed
Lincoff  HStopa  MKreissig  I Ambulatory binocular occlusion. Retina 2004;24 (2) 246- 253
PubMed Link to Article
Meyer-Schwickerath  G Lichtcoagulation: Buch. Augenarzt Klin Monatsbl Augenheilkd 1959;331- 96
Custodis  E Bedeutet die Plombenaufnahung auf die Sclera. Ber Deutsch Ophth Ges 1953;58102
Lincoff  HABaras  J McLean  J Modifications to the Custodis procedure for retinal detachment. Arch Ophthalmol 1965;73160- 163
PubMed Link to Article
Lincoff  H McLean  JM Modifications to the Custodis procedure II: a new silicone implant for large tears. Am J Ophthalmol 1967;64 (5) 877- 879
PubMed
Langston  RLincoff  HA McLean  JM Scleral abscess II: the experimental production in animals. Arch Ophthalmol 1965;74 (5) 665- 668
PubMed Link to Article
Lincoff  HA McLean  JM Cryosurgical treatment of retinal detachment II. Trans Am Acad Ophthalmol Otolaryngol 1966;70 (2) 202- 211
PubMed
Machemer  RNorton  EW A new concept for vitreous surgery 3: indications and results. Am J Ophthalmol 1972;74 (6) 1034- 1056
PubMed
Lincoff  HStopa  MKreissig  I  et al.  Cutting the encircling band. Retina 2006;26 (6) 650- 654
PubMed Link to Article

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