A white, 51-year-old man with pseudophakia but otherwise no significant medical history had a 5-week history of floaters in the left eye. When he arrived at our clinic, his visual acuity was 6/60 in the affected eye with 2 or more cells in the anterior chamber and an IOP of 40 mm Hg. Fundal examination revealed a superior bullous RRD with macular involvement, a subretinal demarcation line, and 2 superotemporal horseshoe tears. As in case 1, the IOP and anterior chamber activity were refractory to treatment, and the patient underwent a nondrainage scleral buckle procedure. An anterior chamber paracentesis was performed for aqueous humor analysis. Nine months after surgery, no anterior chamber activity was detected, and the IOP was normal at 14 mm Hg.