Ketorolac was discontinued 8 months after its institution. Approximately 6 weeks after discontinuing ketorolac, the patient noticed decreased vision in the right eye. Seven weeks after discontinuing ketorolac, his visual acuity had decreased to 20/70. He had a positive Watzke sign. Optical coherence tomography showed an FTMH (Figure 2A). At this time topical nepafenac, 0.1%, was started 4 times per day in the right eye (off-label treatment). Eleven weeks later, his visual acuity had improved to 20/30 and the FTMH was closed on OCT (Figure 2B). To ensure that a very small macular hole was not overlooked, care was taken to image the central fovea each time OCT was performed.