The second case involved a 51-year-old man who underwent surgical removal of an IOFB in the right eye.3 The IOFB was embedded in the ciliary body, and attempts to remove it resulted in hemorrhage that precluded visualization. An air/fluid exchange was performed at 30 mm Hg, which allowed better visualization, and the IOFB was extracted. However, 5 minutes after the air/fluid exchange began, the patient's end-tidal carbon dioxide dropped to 18 mm Hg, along with progressive desaturation and hypotension. The patient was noted to have a millwheel murmur, which is associated with large amounts of intracardiac air. The air infusion was halted, and the eye was closed but the patient developed cardiac arrest. The patient was subsequently identified as having a patent foramen ovale, which allowed air into the arterial circulatory system, resulting in multiple arterial emboli. The patient developed a myocardial infarction and multiple organ failure and died 4 weeks later.