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MULTIPLE EPIDERMOID CARCINOMA OF EYE AND LID

A. H. COCHRAN, M.D.; G. ALLEN ROBINSON, M.D.
Arch Ophthalmol. 1931;5(6):936-942. doi:10.1001/archopht.1931.00820060104010.
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James G., aged 20, was admitted to the eye clinic of Dr. E. S. Thomson in the Manhattan Eye, Ear and Throat Hospital on Jan. 30, 1928, complaining of a growth on the lower right eyelid which had been present for three months. It was increasing in size and slightly tender. The lesion was ulcerated and inflamed, and was 2 cm. long, 1 cm. wide and 0.5 cm. deep. Because of its inflammatory nature it was not thought to be malignant on first examination, and was treated for three days with local applications until the following biopsy report by Dr. Eggston, attending pathologist, was received : "Specimen consists of a small fragment of tissue, 8 by 5 by 4 mm. Section shows greatly proliferated stratified epithelium with marked papillary infiltration and penetration of the stroma. There are numerous mitotic cells and a few epithelial pearls present. Diagnosis : squamous cell epithelioma (malignant)."

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