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MANAGEMENT OF RECURRENT TRACHOMA FOLLOWING SULFANILAMIDE THERAPY:  CHEMOTHERAPY COMBINED WITH IONTOPHORESIS THERAPY AS A PROPHYLACTIC MEASURE AGAINST RECURRENCE

WILLIAM LeGRANDE COOPER, M.D.
Arch Ophthalmol. 1940;24(3):467-472. doi:10.1001/archopht.1940.00870030043004.
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A review of the recent literature with regard to the curative role of sulfanilamide in the treatment of trachoma shows that the data in general rightfully tend to favor the use of this drug. Opinions vary from merely obtaining favorable results to virtually classifying the drug as a specific. Another opinion to be added to the multitudinous clinical reports already published on the subject would be superfluous, but it will suffice to reiterate Lian's1 summary which appropriately delineates the issue as it appears to be viewed to date : "Although sulfanilamide alone will not cure trachoma, it is a valuable aid in combination with the mechanical methods."

It is the purpose here to deal with an important aspect in the management of the disease during occurrences of late relapses after apparently complete cures with sulfanilamide compounds. Emphasis must be laid on this high rate of relapses, so that clinical opinion

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