Experimental Studies on the Trabecular Meshwork in Primates

Arch Ophthalmol. 1963;69(3):335-349. doi:10.1001/archopht.1963.00960040341016.
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There is a considerable amount of information about the normal structure of the trabecular meshwork.* However, little is known about its pathological reactions.2,12,39,40 This paper is an attempt to study the morphological behavior of chamber angle tissue under 3 different conditions: (1) after perfusion of the anterior chamber with various solutions; (2) after autologous implantation into the anterior chamber, and (3) after experimentally elevated intraocular pressure.

Material and Methods  Because of great differences in the structure of the trabecular meshwork between primates and other mammals described previously,37,41 human and monkey eyes only were used in this study. A total of 28 eye-bank eyes and 43 freshly enucleated monkey eyes (Macaca mulatta and Cercopithecus aethiops) were studied.

1. Perfusion Experiments.  —Eighteen monkey and 28 autopsy eyes were perfused with a polyethylene tube fixed to a hypodermic needle. It was thrust through the anterior chamber so that a double perforation


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