A case of thioridazine pigmentary retinopathy was followed-up for a six-year period. The initial insult to the choriocapillaris, pigment epithelium, and photoreceptors caused a progressive alteration in not only the ophthalmoscopic appearance but also the visual function. There was a progressive visual field loss as well as an alteration in the macular electroretinogram. I emphasize the progressive nature of this condition even after the drug has been discontinued. Periodic follow-up examinations are advised.