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March 1979, Vol 97, No. 3 >
ARTICLE | March 1979

HLA Antigens in Ocular Cicatricial Pemphigoid

Bartly J. Mondino, MD; Stuart I. Brown, MD; Bruce S. Rabin, MD, PhD
Arch Ophthalmol. 1979;97(3):479. doi:10.1001/archopht.1979.01020010229007.
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• HLA antigen frequencies were studied in 45 patients with ocular cicatricial pemphigoid. HLA-B12 was found to have an increased frequency of 44.4% in patients with ocular cicatricial pemphigoid, which was statistically significant when compared with a frequency of 19.6% in the control population (P < .001 or P < .031 when corrected for the number of antigens tested). The results of this study suggest that there is an immunogenetic susceptibility to the development of ocular cicatricial pemphigoid.

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