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Leber's Idiopathic Stellate Neuroretinitis

Richard F. Dreyer, MD; Gary Hopen, MD; J. Donald M. Gass, MD; J. Lawton Smith, MD
Arch Ophthalmol. 1984;102(8):1140-1145. doi:10.1001/archopht.1984.01040030918013.
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• Twenty-nine eyes of 27 patients demonstrated the typical features of neuroretinitis with a mascular star. Historical and fluorescein angiographic features of this condition implicate a bloodborne infectious agent. It is likely that multiple agents can produce this condition, including the agent of cat-scratch fever and leptospirosis. A small subgroup may exist in whom this condition resembles anterior ischemic optic neuropathy and has a less favorable clinical course than is usual. There is evidence that this condition is not related to demyelinating disease. It is emphasized that this condition is not a maculopathy since vascular leakage in the optic nerve causes the star. Therefore, we suggest that this condition be renamed Leber's idiopathic stellate neuroretinitis.


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