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Do I Take the Eye Out or Leave It In?

Willem A. Manschot, MD, PhD
Arch Ophthalmol. 1986;104(12):1747-1748. doi:10.1001/archopht.1986.01050240021006.
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To the Editor.  —I read with pleasure the astute editorial with the above-mentioned title by Dr Fine1 in which he commented on the results of cobalt plaque radiotherapy for malignant melanomas reported by Augsburger and colleagues2 in the same issue of the Archives. Following a report by Seddon et al3 that compared the survival times of patients treated either with proton beam irradiation or with enucleation, these authors concluded that, at least for the first three years after treatment, there are no major differences in survival times in patients with melanoma treated either with cobalt plaque irradiation or with enucleation. The authors stated that radiation therapy is preferable because it preserves some vision apparently without increasing mortality. Dr Fine enumerated a series of convincing arguments that raise doubts about whether this statement is correct and that indicate that a prospective, randomized clinical trial is the only


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