My colleagues and I recently reported 11 cases of crystalline deposits on intraocular lenses associated with one viscoelastic.1 Soon after that report, additional cases were brought to my attention.
We have since surveyed the ophthalmologists in the Rocky Mountain area. With 175 responses, we now have 11 additional cases since our initial report. All 11 cases were associated with three different viscoelastics (not only the viscoelastic originally reported). One case of crystalline deposition was associated with a membrane on an intraocular lens that was peeled off the surface of the lens in a gelatinous substrate. These crystalline deposits have calcium as their major component, which would appear to be unrelated to the viscoelastic used.
With 22 cases now documented, obviously, crystallization can occur more frequently than previously suggested. After 18 months, some of our original cases persisted with decreased vision without resolution where the crystals are sequestered against the