In May 2004, as a result of visual loss in his left eye in the absence of pain, the patient consulted his ophthalmologist, who observed flap necrosis at the inferior edge (Figure 1). Lubricant treatment was initiated, and because of poor evolution, the patient was referred to our center for further treatment. At that stage, he had necrosis of the temporal half of the flap associated with anesthesia of the left trigeminal region. The patient was treated successively during the following weeks with artificial tears without preservatives, tear plug, autologous plasma, cyanoacrylate adhesive, amniotic membrane patch, and a bandage contact lens. Two months later, epithelialization was achieved, leaving as a consequence an anterior stromal opacity and notable topographic irregularity (Figure 2), which only permitted a best-corrected visual acuity of less than 20/200, as measured with eyeglasses.