0
ARTICLE |

Ovoid Bodies in Choroidal Neurofibromatosis FREE

Hisako Kurosawa, MD; Akimitsu Kurosawa, MD
[+] Author Affiliations

Accepted for publication Feb 24, 1982.

Reprint requests to Department of Ophthalmology, Niigata University School of Medicine, Asahi-machi 1, Niigata 951, Japan (Dr A. Kurosawa).


Arch Ophthalmol. 1982;100(12):1939-1941. doi:10.1001/archopht.1982.01030040919010
Text Size: A A A
Published online

• We studied the ultrastructure of the ovoid bodies in choroidal neurofibromatosis. Ovoid bodies consisted of groups of the same kind of elongated cells arranged in lamellar patterns. The elongated cell was characterized by a fragmented circumferential basal lamina, groups of pinocytotic vesicles, a desmosomelike intercellular contact, and intimate contact with axons. These findings suggest that elongated cells are proliferated Schwann's cells and ovoid bodies do not correspond with real sensory nerve end organs; rather, they are enlarged peripheral nerves due to neoplastic hyperplasia of Schwann's cells around axons.

REFERENCES

Collins ET, Batten RD:  Neuro-fibroma of the eyeball and its appendages . Trans Ophthalmol Soc UK 1905;;25:248-257.
Wheeler JM:  Plexiform neurofibromatosis (von Recklinghausen's disease) involving choroid, ciliary body and other structures . Am J Ophthalmol 1937;;20:368-375.
Davis FA:  Plexiform neurofibromatosis (Recklinghausen's disease) of orbit and globe with associated glioma of the optic nerve and brain: Report of a case . Arch Ophthalmol 1939;;22:761-791.
Knight MS:  A critical survey of neoplasms of the choroid . Am J Ophthalmol 1925;;8:791-801.
Wolter JR, Gonzales-Sirit R, Mankin WJ:  Neurofibromatosis of the choroid . Am J Ophthalmol 1962;;54:217-225.
Wolter JR:  Nerve fibrils in ovoid bodies with neurofibromatosis of the choroid . Arch Ophthalmol 1965;;73:696-699.
Kurosawa A, Imai A, Nakama T:  A case of neurofibromatosis with unilateral congenital glaucoma . Folia Ophthalmol Jpn 1980;;31:1285-1290.
Nishi K, Oura C, Pallie W:  Fine structure of pacinian corpuscles in the mesentery of the cat . J Cell Biol 1969;;43:539-552.
Pease DC, Pallie W:  Electron microscopy of digital tactile corpuscles and small cutaneous nerves . J Ultrastruct Res 1959;;2:352-365.
Chouchkov CN:  On the fine structure of Krause's bulbs in human skin, oral cavity and rectum . Arch Histol Jpn 1973;;35:365-375.
Weiser G:  An electron microscope study of 'Pacinian neurofibroma.' Virchows Arch Pathol Anat 1975;;366:331-340.
Lassmann H, Jurecka W, Lassmann G, et al:  Different types of benign nerve sheath tumors: Light microscopy, electron microscopy and autoradiography . Virchows Arch Pathol Anat 1977;;375:197-210.

First Page Preview

First page PDF preview

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Collins ET, Batten RD:  Neuro-fibroma of the eyeball and its appendages . Trans Ophthalmol Soc UK 1905;;25:248-257.
Wheeler JM:  Plexiform neurofibromatosis (von Recklinghausen's disease) involving choroid, ciliary body and other structures . Am J Ophthalmol 1937;;20:368-375.
Davis FA:  Plexiform neurofibromatosis (Recklinghausen's disease) of orbit and globe with associated glioma of the optic nerve and brain: Report of a case . Arch Ophthalmol 1939;;22:761-791.
Knight MS:  A critical survey of neoplasms of the choroid . Am J Ophthalmol 1925;;8:791-801.
Wolter JR, Gonzales-Sirit R, Mankin WJ:  Neurofibromatosis of the choroid . Am J Ophthalmol 1962;;54:217-225.
Wolter JR:  Nerve fibrils in ovoid bodies with neurofibromatosis of the choroid . Arch Ophthalmol 1965;;73:696-699.
Kurosawa A, Imai A, Nakama T:  A case of neurofibromatosis with unilateral congenital glaucoma . Folia Ophthalmol Jpn 1980;;31:1285-1290.
Nishi K, Oura C, Pallie W:  Fine structure of pacinian corpuscles in the mesentery of the cat . J Cell Biol 1969;;43:539-552.
Pease DC, Pallie W:  Electron microscopy of digital tactile corpuscles and small cutaneous nerves . J Ultrastruct Res 1959;;2:352-365.
Chouchkov CN:  On the fine structure of Krause's bulbs in human skin, oral cavity and rectum . Arch Histol Jpn 1973;;35:365-375.
Weiser G:  An electron microscope study of 'Pacinian neurofibroma.' Virchows Arch Pathol Anat 1975;;366:331-340.
Lassmann H, Jurecka W, Lassmann G, et al:  Different types of benign nerve sheath tumors: Light microscopy, electron microscopy and autoradiography . Virchows Arch Pathol Anat 1977;;375:197-210.

Correspondence

CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.