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Neuroretinal Rim Area-Reply FREE

Gordon Balazsi, MD; Stephen M. Drance, MD
Arch Ophthalmol. 1984;102(11):1584-1584. doi:10.1001/archopht.1984.01040031283004
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In Reply.  —We are grateful for Dr Sommer's remarks about the neuroretinal rim area in patients with suspected and early chronic glaucoma and for the opportunity to make a few further observations in response.All of us are striving to find an "ideal" marker that would become abnormal before the onset of classic visual field defects and should also become positive before optic nerve damage and generalized axon loss occur. Such a marker would probably give us the best opportunity to take preventive measures at much earlier stages of damage.There is evidence that axons are lost diffusely in the retina before localized visual field loss occurs.1-4 There is also evidence that contrast sensitivity,5 retinal receptive fieldlike functions,6 color disturbance,7 and overall loss of the differential threshold8 precede localized visual field defects. In the case of color disturbances, this value has been shown to be predictive

REFERENCES

Motolko M, Drance SM:  Features of the optic disc in preglaucomatous eyes . Arch Ophthalmol 1981;;99:1992-1994.
Pederson JE, Anderson DR:  The mode of progressive disc cupping in ocular hypertension and glaucoma . Arch Ophthalmol 1980;;98:940-945.
Quigley HA, Addicks EM, Green WR:  Optic nerve damage in human glaucoma: III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy . Arch Ophthalmol 1982;;100:135-146.
Airaksinen J, Drance SM: Diffuse and localized nerve fibre loss in glaucoma. Am J Ophthalmol, in press.
Atkin A, Bodis-Wollner I, Wolkstein M, et al:  Abnormalities of central contrast sensitivity in glaucoma . Am J Ophthalmol 1979;;88:205-211.
Enoch JM, Campos EC:  Analysis of patients with open angle glaucoma using perimetric techniques reflecting receptive field-like properties . Doc Ophthalmol 1978;;173:137-149.
Lakowski R, Drance SM:  Acquired dischromatopsia: The earliest functional losses in glaucoma . Doc Ophthalmol Proc Ser 1979;;19:159-165.
Anctil J-L, Anderson DR:  Early foveal involvement and generalized depression of the visual field in glaucoma . Arch Ophthalmol 1984;;102:363-370.
Drance SM, Lakowski R, Schulzer M, et al:  Acquired color vision changes in glaucoma: Use of 100-hue test and Pickford anomaloscope as predictors of glaucomatous field change . Arch Ophthalmol 1981;;99:829-831.

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Motolko M, Drance SM:  Features of the optic disc in preglaucomatous eyes . Arch Ophthalmol 1981;;99:1992-1994.
Pederson JE, Anderson DR:  The mode of progressive disc cupping in ocular hypertension and glaucoma . Arch Ophthalmol 1980;;98:940-945.
Quigley HA, Addicks EM, Green WR:  Optic nerve damage in human glaucoma: III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy . Arch Ophthalmol 1982;;100:135-146.
Airaksinen J, Drance SM: Diffuse and localized nerve fibre loss in glaucoma. Am J Ophthalmol, in press.
Atkin A, Bodis-Wollner I, Wolkstein M, et al:  Abnormalities of central contrast sensitivity in glaucoma . Am J Ophthalmol 1979;;88:205-211.
Enoch JM, Campos EC:  Analysis of patients with open angle glaucoma using perimetric techniques reflecting receptive field-like properties . Doc Ophthalmol 1978;;173:137-149.
Lakowski R, Drance SM:  Acquired dischromatopsia: The earliest functional losses in glaucoma . Doc Ophthalmol Proc Ser 1979;;19:159-165.
Anctil J-L, Anderson DR:  Early foveal involvement and generalized depression of the visual field in glaucoma . Arch Ophthalmol 1984;;102:363-370.
Drance SM, Lakowski R, Schulzer M, et al:  Acquired color vision changes in glaucoma: Use of 100-hue test and Pickford anomaloscope as predictors of glaucomatous field change . Arch Ophthalmol 1981;;99:829-831.

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