Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
A 76-year-old woman experienced sudden painless visual loss in her left eye. Visual acuity was 20/40 OD and 20/30 OS. On fundus examination, the right eye had occult neovascularization and the left eye showed a small epipapillary hemorrhage. No retinal inflammatory infiltrates were identified. Fluorescein angiography of the left eye demonstrated an extrafoveolar neovascular membrane and a large peripapillary and macular hypofluorescence without late staining (Figure, A). Thermal laser photocoagulation was performed in the left eye. The patient had an atrial fibrillation already documented, the hemostasis parameters were under control with coumarin derivatives, and the patient did not have giant cell arteritis. The patient developed successive recurrent large neovascular membranes that correlated nicely with the initial areas of choroidal hypofluorescence (Figure, B-D).
Fluorescein angiography of a 76-year-old woman who experienced sudden painless visual loss in her left eye. A, Acute peripapillary and central hypofluorescence (arrowheads) and first choroidal neovascularization (arrow) in the left eye. At 1 month (B), 3 months (C), and 6 months (D), laser scar (arrowheads) was visible, and extension of the choroidal neovascular front (arrows) eventually correlated with the overall initial area of presumed choroidal hypoperfusion.
Choroidal hypofluorescence was interpreted as a choroidal hypo- perfusion because there was no clinical retinal opacification to suggest blockage of background fluorescence and because no late staining was identified on the angiogram.
Ischemia has been implied as one of the numerous factors triggering choroidal neovascularization.1 - 2 The evident correlation between the initial area of presumed acute choroidal ischemia and the eventual extent of choroidal neovascularization may lend support to this hypothesis in our case.
Correspondence: Dr Guagnini, Department of Ophthalmology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Ave Hippocrate 10, B-1200 Brussels, Belgium (ann-pascale.guagnini@ofta.ucl.ac.be).
Financial Disclosure: None reported.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
Instructions
Comments are moderated and will appear on the site at the discretion of the Archives of Ophthalmology editors. Comments should not exceed 500 words of text and 10 references.
Do not submit personal medical questions or information that could identify a specific patient, questions about a particular case, or general inquiries to an author. Only content that has not been published, posted, or submitted elsewhere should be submitted. By submitting this Comment, you and any coauthors transfer copyright to the journal if your Comment is posted.
* = Required Field
Disclosure of Any Conflicts of Interest* Indicate all relevant conflicts of interest of each author below, including all relevant financial interests, activities, and relationships within the past 3 years including, but not limited to, employment, affiliation, grants or funding, consultancies, honoraria or payment, speakers’ bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued. If all authors have none, check "No potential conflicts or relevant financial interests" in the box below. Please also indicate any funding received in support of this work. The information will be posted with your response.
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 2
Customize your page view by dragging & repositioning the boxes below.
and access these and other features:
Register Now
Enter your username and email address. We'll send you a reminder to the email address on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.