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Correspondence |

Regarding Registration of Clinical Trials

Anja M. Palmowski-Wolfe, MD
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Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

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Arch Ophthalmol. 2007;125(6):853-853. doi:10.1001/archopht.125.6.853-a
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It is with great interest that I read the editorial by Levin et al1 on the registration of clinical trials in the September 2005 issue of the Archives.

It is not quite clear to me how registering studies will improve ethics—unless there is a controlling agency that makes sure the results of each study will be submitted and then also accepted for publication (so far, negative results are much less likely to be accepted for publication by reviewers).

Another concern that I am sure Levin and colleagues will have thought about involves intellectual property. Once a study design is published, how do you prevent others from doing the same or a similar study that may then get published first?

AUTHOR INFORMATION

Correspondence: Dr Palmowski-Wolfe, University Eye Hospital Basel, Mittlere Strasse Basel, Basel 4012, Switzerland (palmowskia@uhbs.ch).

Financial Disclosure: None reported.

REFERENCES

Levin  LA, Gottlieb  JL, Beck  RW.  et al.  Registration of clinical trials. Arch Ophthalmol 2005;1231263- 1264
PubMed

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Levin  LA, Gottlieb  JL, Beck  RW.  et al.  Registration of clinical trials. Arch Ophthalmol 2005;1231263- 1264
PubMed

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