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Blind Eyes With Occult Malignant Melanoma

Mordechai Rosner, MD
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Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

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Arch Ophthalmol. 2009;127(9):1227-1227. doi:10.1001/archophthalmol.2009.227
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The article by Eagle et al1 and the editorial in reference to it2 are most important, and obviously will change the surgical management of blind, painful eyes. This article has far wider clinical implications than just indicating the danger in eviscerating eyes with occult neoplasia.

An intraocular malignant melanoma is also life threatening when no evisceration is performed. Thus, it should be stressed that all patients with blind eyes should undergo monitoring for occult neoplasm periodically, not only before surgery. B-scan ultrasound should be used whenever the media is opaque. Moreover, when the results are inconclusive, the possibility of occult intraocular neoplasia may be an indication for enucleation, even when the blind eye is not painful.

The same evaluation should be performed before enucleation as before evisceration. Leaving a malignant tumor in the orbit is as dangerous after enucleation as after evisceration. Enucleated eyes should be carefully inspected after they are removed, and any areas suspected of extraocular tumor extrusion should be examined by frozen sections. If findings are positive, orbital biopsies are indicated, and even exenteration, according to the results.

It is most important to collect data on hidden neoplasm in blind eyes so their prevalence will be known.

Personally, I prefer performing evisceration over enucleation in all cases when the possibility of hidden intraocular tumor is excluded. Evisceration is shorter in duration than enucleation, and the results are good. In patients who could not undergo surgery with general anesthesia, evisceration was performed using retrobulbar anesthesia, though I would not suggest this for enucleation.

AUTHOR INFORMATION

Correspondence: Dr Rosner, The Goldschleger Eye Institute, Tel-Aviv University, Sackler Faculty of Medicine, Sheba Medical Center, 52621 Tel-Hashomer, Israel (mrosner@post.tau.ac.il).

Financial Disclosure: None reported.

REFERENCES

Eagle  RC  Jr, Grossniklaus  HE, Syed  N, Hogan  RN, Lloyd  WC  III, Folberg  R. Inadvertent evisceration of eyes containing uveal melanoma. Arch Ophthalmol 2009;127 (2) 141- 145
PubMed
Schefler  AC, Abramson  DH. Should evisceration ever be done in a blind, painful eye? Arch Ophthalmol 2009;127 (2) 211- 212
PubMed

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Eagle  RC  Jr, Grossniklaus  HE, Syed  N, Hogan  RN, Lloyd  WC  III, Folberg  R. Inadvertent evisceration of eyes containing uveal melanoma. Arch Ophthalmol 2009;127 (2) 141- 145
PubMed
Schefler  AC, Abramson  DH. Should evisceration ever be done in a blind, painful eye? Arch Ophthalmol 2009;127 (2) 211- 212
PubMed

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