Author Affiliations: L.V. Prasad Eye Institute, Hyderabad, India.
We read the article by Almeida et al1 with interest. There are a few overlooked issues that we would like to highlight.
The authors have attempted to examine the relationship between anterior chamber sterilization and vitreous positivity rate in endophthalmitis, with implications for postcataract surgery endophthalmitis. However, the sample selected by them includes a heterogenous population of both endogenous and exogenous cases of endophthalmitis. The mechanism of entry of microorganisms is specific in the case of cataract surgery, as opposed to posttraumatic or endogenous cases. Inclusion of these cases confounds the data, as the microbiological profile, load, and route of entry is not comparable. Analysis of this diverse population and interpretation of the results for postcataract surgery endophthalmitis would be extrapolation beyond the data.
Moreover, endogenous cases, which present with progressive vitritis, would be expected to have increased microbiological load in the vitreous and not in the anterior chamber. The reverse would be expected in postsurgical or posttraumatic cases. It would have been useful to classify their samples based on the clinical information from the cases and analyze each group separately.
Correspondence: Dr Murthy, L.V. Prasad Eye Institute, Kallam Anji Reddy Campus, L.V. Prasad Marg, Banjara Hills, Hyderbad 500034, Andhra Pradesh, India (smurthy@lvpei.org).
Financial Disclosure: None reported.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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