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ARTICLE |

CLINICAL STUDY OF EFFECT OF TOBACCO ON THE NORMAL ANGIOSCOTOMA FREE

AUSTIN I. FINK, M.D.
[+] Author Affiliations

Read at a meeting of the Brooklyn Ophthalmological Society April 19, 1945.


Arch Ophthalmol. 1946;35(1):15-19. doi:10.1001/archopht.1946.00890200019003
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In 1926 the classic form of the angioscotoma was first described.1 This work has been a source of aid to clinicians investigating disease of the nasal accessory sinuses,2 forms of edema,3 glaucoma4 and menstrual disturbances.5 The research worker, too, has had recourse to angioscotometry in studying the effects of sulfanilamide,6 inhalation of oxygen,7 and amphetamine sulfate,8 and studies of the effects on the visual fields of high altitude9 have been a basis of investigations in World War II. No effort has been made, however, to determine the effect of smoking on the normal angioscotoma. Since tobacco smoking is so widespread, it was thought that knowledge of its effect might be of clinical and experimental value. It was therefore decided to study the effect on the central visual fields of smoking 1 cigaret with inhalation.

METHODS AND MATERIAL  Angioscotometry was the method

REFERENCES

Evans, J. N.:  A Preliminary Report of the Retinal Vessel Scotoma , Am. J. Ophth. 9:118-119 ( (Feb.) ) 1926;.
Evans, J. N.:  Application of Angioscotometry to the Study of Nasal Accessory Sinus Disease , Ann. d'ocul. 169:717-730 ( (Sept.) ) 1932;.
Evans, J. N.:  The Scotometry of Retinal Edema , Am. J. Ophth. 16:417-424 ( (May) ) 1933;.
Evans, J. N.:  Transient Fluctuations in the Scotoma of Glaucoma , Am. J. Ophth. 18:333-347 ( (April) ) 1935;.
Evans, J. N.:  A Scotoma Associated with Menstruation , Am. J. Ophth. 24:507-519 ( (May) ) 1941;.
Rosenthal, C. M.:  Changes in Angioscotomas Associated with the Administration of Sulphanilamide , Arch. Ophth. 22:73-81 ( (July) ) 1939;.
Rosenthal, C. M.:  Changes in Angioscotomas Associated with the Inhalation of Oxygen , Arch. Ophth. 22:385-392 ( (Sept.) ) 1939;.
Rosenthal, C. M., and Seitz, C. P.:  Alterations in Angioscotomas Following the Oral Administration of Benzedrine Sulphate , Am. J. Ophth. 23:545-549 ( (May) ) 1940;.
Evans, J. N., and McFarland, R. A.:  Effects of Oxygen Deprivation on Visual Fields , Am. J. Ophth. 21:968-980 ( (Sept.) ) 1938;.
Evans, J. N.:  Angioscotometry , Am. J. Ophth. 9:489-506 ( (July) ) 1926;
Evans, J. N.: Clinical Scotometry , New Haven, Conn., Yale University Press, 1937;.
Goodman, L., and Gilman, A.: The Pharmacological Basis of Therapeutics , New York, The Macmillan Company, 1941;,
Herrell, W. E., and Cusick, P. L.:  Vascular and Retinal Abnormalities Following Inhalation of Tobacco Smoke , Proc. Staff Meet., Mayo Clin. 13:273 ( (May 4) ) 1938;.
Evans, W. F., and Stewart, H. J.:  The Effect of Smoking Cigarettes on the Peripheral Blood Flow , Am. Heart J. 26:78-91 ( (July) ) 1943;.
Weatherby, J. H.:  Skin Temperature Changes Caused by Smoking and Other Sympathomimetic Stimuli , Am. Heart J. 24:17-30 ( (July) ) 1942;.
Main, R. J.:  Acute Effects of Smoking on Respiration and Circulation , Proc. Soc. Exper. Biol. & Med. 48:495-500 ( (Nov.) ) 1941;.
Haag, H. B., and Larson, P. S.:  Some Chemical and Pharmacological Observations on "Low Nicotine" Tobacco , Science 97:187-188 ( (Feb. 19) ) 1943;.
Main.16 Weatherby.15 Haag and Larson.17

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Evans, J. N.:  A Preliminary Report of the Retinal Vessel Scotoma , Am. J. Ophth. 9:118-119 ( (Feb.) ) 1926;.
Evans, J. N.:  Application of Angioscotometry to the Study of Nasal Accessory Sinus Disease , Ann. d'ocul. 169:717-730 ( (Sept.) ) 1932;.
Evans, J. N.:  The Scotometry of Retinal Edema , Am. J. Ophth. 16:417-424 ( (May) ) 1933;.
Evans, J. N.:  Transient Fluctuations in the Scotoma of Glaucoma , Am. J. Ophth. 18:333-347 ( (April) ) 1935;.
Evans, J. N.:  A Scotoma Associated with Menstruation , Am. J. Ophth. 24:507-519 ( (May) ) 1941;.
Rosenthal, C. M.:  Changes in Angioscotomas Associated with the Administration of Sulphanilamide , Arch. Ophth. 22:73-81 ( (July) ) 1939;.
Rosenthal, C. M.:  Changes in Angioscotomas Associated with the Inhalation of Oxygen , Arch. Ophth. 22:385-392 ( (Sept.) ) 1939;.
Rosenthal, C. M., and Seitz, C. P.:  Alterations in Angioscotomas Following the Oral Administration of Benzedrine Sulphate , Am. J. Ophth. 23:545-549 ( (May) ) 1940;.
Evans, J. N., and McFarland, R. A.:  Effects of Oxygen Deprivation on Visual Fields , Am. J. Ophth. 21:968-980 ( (Sept.) ) 1938;.
Evans, J. N.:  Angioscotometry , Am. J. Ophth. 9:489-506 ( (July) ) 1926;
Evans, J. N.: Clinical Scotometry , New Haven, Conn., Yale University Press, 1937;.
Goodman, L., and Gilman, A.: The Pharmacological Basis of Therapeutics , New York, The Macmillan Company, 1941;,
Herrell, W. E., and Cusick, P. L.:  Vascular and Retinal Abnormalities Following Inhalation of Tobacco Smoke , Proc. Staff Meet., Mayo Clin. 13:273 ( (May 4) ) 1938;.
Evans, W. F., and Stewart, H. J.:  The Effect of Smoking Cigarettes on the Peripheral Blood Flow , Am. Heart J. 26:78-91 ( (July) ) 1943;.
Weatherby, J. H.:  Skin Temperature Changes Caused by Smoking and Other Sympathomimetic Stimuli , Am. Heart J. 24:17-30 ( (July) ) 1942;.
Main, R. J.:  Acute Effects of Smoking on Respiration and Circulation , Proc. Soc. Exper. Biol. & Med. 48:495-500 ( (Nov.) ) 1941;.
Haag, H. B., and Larson, P. S.:  Some Chemical and Pharmacological Observations on "Low Nicotine" Tobacco , Science 97:187-188 ( (Feb. 19) ) 1943;.
Main.16 Weatherby.15 Haag and Larson.17

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