0
ARTICLE |

Experimental Herpes Simplex Uveitis: Title and subTitle BreakThe Isolation of Herpesvirus in an Iris Organ Culture System FREE

David N. Tucker, MD; Albert Z. Kapikian, MD
[+] Author Affiliations

Submitted for publication June 30, 1969.

Reprint requests to Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Bethesda, Md (Dr. Kapikian).


Arch Ophthalmol. 1969;82(6):827-829. doi:10.1001/archopht.1969.00990020819018
Text Size: A A A
Published online

Experimental herpes simplex uveitis was induced in rabbits within three days following anterior chamber inoculation of herpes simplex virus. The reisolation of this virus from aqueous humor specimens of these animals was achieved in both rabbit iris organ cultures and WI38 cell cultures. The sensitivity of virus recovery in both these virologic systems was compared.

REFERENCES

Kaufman, H.E.:  The Uvea , Arch Ophthal 75:407-434 ( (March) ) 1966;.
Martenet, A.C.:  Herpes Simplex Uveitis: An Experimental Study , Arch Ophthal 76:858-865 ( (Dec) ) 1966;.
Hewson, G.E.:  Iritis Due to Herpes Virus , Irish J Med Sci 6:372-373 ( (Aug) ) 1957;.
Sezer, F.N.:  The Isolation of a Virus as the Cause of Behcet's Disease , Amer J Ophthal 36:301-315 ( (March) ) 1953;.
Kimura, S.J.:  Experimental Herpes Simplex Uveitis , Amer J Ophthal 49:627 ( (March) ) 1960;.
Tucker, D.N., and Kapikian, A.Z.:  Viral Growth Patterns in an Iris Organ Culture System , Arch Ophthal 82:372-376 ( (Sept) ) 1969;.
Leibovitz, A.:  The Growth and Maintenance of Tissue-Cell Cultures in Free Gas Exchange With the Atmosphere , Amer J Hyg 78:173-180 ( (Sept) ) 1963;.
Sever, J.L.:  Application of a Microtechnique to Viral Serological Investigations , J Immun 88:320-329 ( (May) ) 1962;.
Pettit, T.H., et al:  Herpes Simplex Uveitis: An Experimental Study With the Fluorescein-Labeled Antibody Technique , Invest Ophthal 4:349-357 ( (June) ) 1965;.
Witmer, R., and Iwamato, T.:  Electron Microscopic Observation of Herpes-like Particles in the Iris , Arch Ophthal 79:331-337 ( (March) ) 1968;.
Tyrrell, D.A.J., and Bynoe, M.L.:  Cultivation of a Novel Type of Common-Cold Virus in Organ Cultures , Brit Med J 1:1467-1470 ( (June 5) ) 1965;.
McIntosh, K., et al:  Recovery in Tracheal Organ Cultures of Novel Viruses From Patients With Respiratory Diseases , Proc Nat Acad Sci 57:933-940 ( (April) ) 1967;.
Higgins, P.G.:  The Isolation of Viruses From Acute Respiratory Infections , Monthly Bull Minist Health 25:283-288 ( (Dec) ) 1966;.

First Page Preview

First page PDF preview

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Kaufman, H.E.:  The Uvea , Arch Ophthal 75:407-434 ( (March) ) 1966;.
Martenet, A.C.:  Herpes Simplex Uveitis: An Experimental Study , Arch Ophthal 76:858-865 ( (Dec) ) 1966;.
Hewson, G.E.:  Iritis Due to Herpes Virus , Irish J Med Sci 6:372-373 ( (Aug) ) 1957;.
Sezer, F.N.:  The Isolation of a Virus as the Cause of Behcet's Disease , Amer J Ophthal 36:301-315 ( (March) ) 1953;.
Kimura, S.J.:  Experimental Herpes Simplex Uveitis , Amer J Ophthal 49:627 ( (March) ) 1960;.
Tucker, D.N., and Kapikian, A.Z.:  Viral Growth Patterns in an Iris Organ Culture System , Arch Ophthal 82:372-376 ( (Sept) ) 1969;.
Leibovitz, A.:  The Growth and Maintenance of Tissue-Cell Cultures in Free Gas Exchange With the Atmosphere , Amer J Hyg 78:173-180 ( (Sept) ) 1963;.
Sever, J.L.:  Application of a Microtechnique to Viral Serological Investigations , J Immun 88:320-329 ( (May) ) 1962;.
Pettit, T.H., et al:  Herpes Simplex Uveitis: An Experimental Study With the Fluorescein-Labeled Antibody Technique , Invest Ophthal 4:349-357 ( (June) ) 1965;.
Witmer, R., and Iwamato, T.:  Electron Microscopic Observation of Herpes-like Particles in the Iris , Arch Ophthal 79:331-337 ( (March) ) 1968;.
Tyrrell, D.A.J., and Bynoe, M.L.:  Cultivation of a Novel Type of Common-Cold Virus in Organ Cultures , Brit Med J 1:1467-1470 ( (June 5) ) 1965;.
McIntosh, K., et al:  Recovery in Tracheal Organ Cultures of Novel Viruses From Patients With Respiratory Diseases , Proc Nat Acad Sci 57:933-940 ( (April) ) 1967;.
Higgins, P.G.:  The Isolation of Viruses From Acute Respiratory Infections , Monthly Bull Minist Health 25:283-288 ( (Dec) ) 1966;.

Correspondence

CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.