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Nanophthalmos With Uveal Effusion: Title and subTitle BreakA New Clinical Entity FREE

Robert J. Brockhurst, MD
[+] Author Affiliations

Submitted for publication June 27, 1974.

This paper was accepted as a thesis in partial fulfillment of the requirements for membership in the American Ophthalmological Society.

Reprint requests to Department of Retina Research, Retina Foundation and the Retina Associates, 100 Charles River Plaza, Boston, MA 02114 (Dr Brockhurst).


Arch Ophthalmol. 1975;93(12):1289-1299. doi:10.1001/archopht.1975.01010020923001
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• Five patients exhibited the association of nanophthalmos and uveal effusion, apparently on a familial basis. Glaucoma, occurring in the fourth to sixth decades of life, required surgical intervention that was followed by the development of secondary retinal and choroidal detachment. Recognition of this syndrome is important because: (1) surgical procedures for glaucoma should be avoided, if possible, in order to prevent the development of uveal effusion; (2) retinal detachment surgical procedures are ineffective in uveal effusion and should be avoided, and (3) choroidal elevation occurring in the uveal effusion phase may be erroneously diagnosed as an intraocular tumor and unnecessary enucleation may follow.

REFERENCES

Black M:  Twins with high hyperopia . Am J Ophthalmol 7:375-376, 1924;.
Southgate PT:  High hypermetropia . Am J Ophthalmol 33:466-467, 1950;.
Witmer R:  Hohe Hypermetropie und Ablatio . Ophthalmologica 121:178-179, 1951;.
Hatcher WF:  Extreme axial hyperopia . Arch Ophthalmol 48:161-162, 1952;.
Manning EL:  Severe hyperopia . Am J Ophthalmol 36:983, 1953;.
Rathschüler R, Dufour R:  Pathologie de l'hypermétropie forte: Périphlébite et décollement de la rétine , Ophthalmologica 129:327-330, 1955;.
Vetter J:  Ablatio retinae als Zweiterkränkung bei Mikrophthalmus und Glaukom . Klin Monatsbl f Augenh 134:421-426, 1959;.
Zuccoli A:  Neuer Beitrag zum Bild der Makrozysten bei der hohen Hypermetropie . Ophthalmologica 145:419-424, 1963;.
Duke-Elder S: System of Ophthalmology . St. Louis, Mo, CV Mosby Co, 1963;, vol 3, pp 488-495.
Schepens CL, Brockhurst RJ:  Uveal effusion: I. Clinical picture . Arch Ophthalmol 70:189-201, 1963;.
Godtfredsen E:  Investigations into hyaluronic acid and hyaluronidase in the subretinal fluid in retinal detachment, partly due to ruptures and partly secondary to malignant choroidal melanoma . Br J Ophthalmol 33:721-732, 1949;.
Sweeney B, in discussion, Schepens CL and Regan CDJ (eds): Controversial Aspects of the Management of Retinal Detachment. Boston, Little Brown & Co, 1965;, pp 315-316.
O'Grady RB:  Nanophthalmos . Am J Ophthalmol 71:1251-1253, 1971;.
Brockhurst RJ, Lam KW:  Uveal effusion: II. Case report with analysis of subretinal fluid . Arch Ophthalmol 90:399-401, 1973;.

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Black M:  Twins with high hyperopia . Am J Ophthalmol 7:375-376, 1924;.
Southgate PT:  High hypermetropia . Am J Ophthalmol 33:466-467, 1950;.
Witmer R:  Hohe Hypermetropie und Ablatio . Ophthalmologica 121:178-179, 1951;.
Hatcher WF:  Extreme axial hyperopia . Arch Ophthalmol 48:161-162, 1952;.
Manning EL:  Severe hyperopia . Am J Ophthalmol 36:983, 1953;.
Rathschüler R, Dufour R:  Pathologie de l'hypermétropie forte: Périphlébite et décollement de la rétine , Ophthalmologica 129:327-330, 1955;.
Vetter J:  Ablatio retinae als Zweiterkränkung bei Mikrophthalmus und Glaukom . Klin Monatsbl f Augenh 134:421-426, 1959;.
Zuccoli A:  Neuer Beitrag zum Bild der Makrozysten bei der hohen Hypermetropie . Ophthalmologica 145:419-424, 1963;.
Duke-Elder S: System of Ophthalmology . St. Louis, Mo, CV Mosby Co, 1963;, vol 3, pp 488-495.
Schepens CL, Brockhurst RJ:  Uveal effusion: I. Clinical picture . Arch Ophthalmol 70:189-201, 1963;.
Godtfredsen E:  Investigations into hyaluronic acid and hyaluronidase in the subretinal fluid in retinal detachment, partly due to ruptures and partly secondary to malignant choroidal melanoma . Br J Ophthalmol 33:721-732, 1949;.
Sweeney B, in discussion, Schepens CL and Regan CDJ (eds): Controversial Aspects of the Management of Retinal Detachment. Boston, Little Brown & Co, 1965;, pp 315-316.
O'Grady RB:  Nanophthalmos . Am J Ophthalmol 71:1251-1253, 1971;.
Brockhurst RJ, Lam KW:  Uveal effusion: II. Case report with analysis of subretinal fluid . Arch Ophthalmol 90:399-401, 1973;.

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