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Vitreous Membranes: Title and subTitle BreakA Light and Electron Microscopical Study FREE

Richard S. Smith, MD; W. A. J. van Heuven, MD; Barbara Streeten, MD
[+] Author Affiliations

Accepted for publication Jan 26, 1976.

Reprint requests to Albany Medical College, Albany, NY 12208 (Dr Smith).


Arch Ophthalmol. 1976;94(9):1556-1560. doi:10.1001/archopht.1976.03910040390014
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• Patients with pigmented vitreous membranes were subjected to partial vitrectomy, and the membranes were studied by light and electron microscopy. Two yellow ochre membranes from eyes removed at autopsy were also examined. The membranes were composed of degenerating red cells and a delicate matrix of collagen. Phagocytic cells of uncertain origin and migrating retinal pigment epithelial cells were present in some of the membranes. Vascular channels were observed in only two cases, in which the membranes had clinical features different from those in the remaining cases. The development of new techniques of vitrectomy and the relatively normal clinical appearance of the posterior pole of the retina in these cases both suggest the potential clinical value of vitreous membrane excision. Additional histopathologic studies of vitrectomy specimens will enhance our understanding of the indications for this procedure.

REFERENCES

Freeman HM:  Recent advances in vitreous surgery . Invest Ophthalmol 12:549-551, 1973;.
van Heuven WAJ, Smith RS:  Results of partial vitrectomy in advanced diabetic retinopathy . Mod Probl Ophthalmol 12:394-399, 1974;.
van Heuven WAJ:  Experiences with partial vitrectomy in patients with proliferative diabetic retinopathy . Mod Probl Ophthalmol 10:684-689, 1972;.
McPherson A (ed): New and Controversial Aspects of Vitreo-Retinal Surgery. St Louis, CV Mosby Co, to be published.
Smith RS, Rudt LA:  Ultrastructural studies of the blood-aqueous barrier: 2. The barrier to horseradish peroxidase in primates . Am J Ophthalmol 76:937-947, 1973;.
Samuels B:  Opacities of the vitreous . Arch Ophthalmol 4:838-857, 1930;.
Gray WA:  Cellular response of vitreous humor to injection of bacteria, blood and vital dyes . J Pathol Bacteriol 37:137-148, 1933;.
Michaelson IC:  Transscleral division of midvitreous membrane under visual control . Br J Ophthalmol 44:634-635, 1960;.
Wadsworth JAC:  Symposium: Retinal detachment, etiology, and pathology . Trans Am Acad Ophthalmol Otolaryngol 56:370-397, 1952;.
Dodo T:  "Window-making" procedure for post-hemorrhagic vitreous membrane . Acta Soc Ophthalmol Jap 68:811-825, 1964;.
Feeney L, Burns RP, Mixon RM:  Human subretinal fluid: Its cellular and subcellular components . Arch Ophthalmol 93:62-69, 1975;.
Wolter JR:  The macrophages of the human vitreous body . Am J Ophthalmol 49:1185-1193, 1960;.
Gloor BP:  On the question of the origin of macrophages in the retina and the vitreous following photocoagulation (autoradiographic investigations by means of 3H-thymidine) . Albrecht von Graefes Arch Klin Ophthalmol 190:183-194, 1974;.
Smith RS, Berson EL:  Acute toxic effects of chloroquine on the cat retina . Invest Ophthalmol 10:237-246, 1971;.
Freilich DB, Lee PF, Freeman HM;  Experimental retinal detachment . Arch Ophthalmol 76:432-436, 1966;.
Constable IJ, Oguri M, Chesney CM, et al:  Platelet-induced vitreous membrane formation . Invest Ophthalmol 12:680-685, 1975;.
Lam KW, Ashrafzadeh MT, Lee CB:  Vitreous membranes: Induction in rabbits by intravitreous leukocyte injections . Arch Ophthalmol 88:655-658, 1972;.
Kattlove HE, Gomez MH:  Studies on the mechanism of ristocetin-induced platelet aggregation . Blood 45:91-96, 1975;.

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Freeman HM:  Recent advances in vitreous surgery . Invest Ophthalmol 12:549-551, 1973;.
van Heuven WAJ, Smith RS:  Results of partial vitrectomy in advanced diabetic retinopathy . Mod Probl Ophthalmol 12:394-399, 1974;.
van Heuven WAJ:  Experiences with partial vitrectomy in patients with proliferative diabetic retinopathy . Mod Probl Ophthalmol 10:684-689, 1972;.
McPherson A (ed): New and Controversial Aspects of Vitreo-Retinal Surgery. St Louis, CV Mosby Co, to be published.
Smith RS, Rudt LA:  Ultrastructural studies of the blood-aqueous barrier: 2. The barrier to horseradish peroxidase in primates . Am J Ophthalmol 76:937-947, 1973;.
Samuels B:  Opacities of the vitreous . Arch Ophthalmol 4:838-857, 1930;.
Gray WA:  Cellular response of vitreous humor to injection of bacteria, blood and vital dyes . J Pathol Bacteriol 37:137-148, 1933;.
Michaelson IC:  Transscleral division of midvitreous membrane under visual control . Br J Ophthalmol 44:634-635, 1960;.
Wadsworth JAC:  Symposium: Retinal detachment, etiology, and pathology . Trans Am Acad Ophthalmol Otolaryngol 56:370-397, 1952;.
Dodo T:  "Window-making" procedure for post-hemorrhagic vitreous membrane . Acta Soc Ophthalmol Jap 68:811-825, 1964;.
Feeney L, Burns RP, Mixon RM:  Human subretinal fluid: Its cellular and subcellular components . Arch Ophthalmol 93:62-69, 1975;.
Wolter JR:  The macrophages of the human vitreous body . Am J Ophthalmol 49:1185-1193, 1960;.
Gloor BP:  On the question of the origin of macrophages in the retina and the vitreous following photocoagulation (autoradiographic investigations by means of 3H-thymidine) . Albrecht von Graefes Arch Klin Ophthalmol 190:183-194, 1974;.
Smith RS, Berson EL:  Acute toxic effects of chloroquine on the cat retina . Invest Ophthalmol 10:237-246, 1971;.
Freilich DB, Lee PF, Freeman HM;  Experimental retinal detachment . Arch Ophthalmol 76:432-436, 1966;.
Constable IJ, Oguri M, Chesney CM, et al:  Platelet-induced vitreous membrane formation . Invest Ophthalmol 12:680-685, 1975;.
Lam KW, Ashrafzadeh MT, Lee CB:  Vitreous membranes: Induction in rabbits by intravitreous leukocyte injections . Arch Ophthalmol 88:655-658, 1972;.
Kattlove HE, Gomez MH:  Studies on the mechanism of ristocetin-induced platelet aggregation . Blood 45:91-96, 1975;.

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