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ARTICLE |

A Simplified Test of Epinephrine Responsiveness FREE

Michael A. Kass, MD; Bernard Becker, MD
[+] Author Affiliations

Accepted for publication Sept 20, 1977.

Reprint requests to the Glaucoma Center, Department of Ophthalmology, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110 (Dr Kass).


Arch Ophthalmol. 1978;96(6):999-1000. doi:10.1001/archopht.1978.03910050523003
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• Forty-three ocular hypertensive and 33 ocular normotensive subjects received two doses of topical 1% epinephrine hydrochloride in one eye. The epinephrine was administered twice, ie, at time "zero" (8 am) and 12 hours later (at 8 pm). The mean intraocular pressure responses at four hours and at 24 hours (12 hours after the last dose of epinephrine) were significantly correlated, r = 0.59 (P <.001). This suggested that the simpler four-hour test was an equally accurate measure of the ocular responsiveness to topical epinephrine.

REFERENCES

Becker B, Shin DH:  Response to topical epinephrine: A practical prognostic test in patients with ocular hypertension . Arch Ophthalmol 94:2057-2058, 1976;.
Shin DH, Kass MA, Becker B:  Intraocular pressure response to topical epinephrine and HLA-B12 . Arch Ophthalmol , 96:1012-1013, 1978;.
Kass MA, Shin DH, Cooper DG, et al:  The ocular hypotensive effect of epinephrine in high and low corticosteroid responders . Invest Ophthalmol 16:530-532, 1977;.
Shin DH, Becker B:  The prognostic value of HLA-B12 and HLA-B7 antigens in patients with increased intraocular pressure . Am J Ophthalmol 82:871-874, 1976;.
Wilensky JT, Podos SM:  Prognostic parameters in primary open-angle glaucoma , in Symposium on Glaucoma: Transactions of the New Orleans Academy of Ophthalmology . St Louis, CV Mosby Co, 1975;, pp 7-30.
Havener W: Ocular Pharmacology , ed 3. St Louis, CV Mosby Co, 1974;, pp 214-223.
Duke-Elder S:  Diseases of the Lens and Vitreous: Glaucoma and Hypotony , vol 11, in Duke-Elder S (ed): System of Ophthalmology . St Louis, CV Mosby Co, 1969;, pp 516-518.

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Becker B, Shin DH:  Response to topical epinephrine: A practical prognostic test in patients with ocular hypertension . Arch Ophthalmol 94:2057-2058, 1976;.
Shin DH, Kass MA, Becker B:  Intraocular pressure response to topical epinephrine and HLA-B12 . Arch Ophthalmol , 96:1012-1013, 1978;.
Kass MA, Shin DH, Cooper DG, et al:  The ocular hypotensive effect of epinephrine in high and low corticosteroid responders . Invest Ophthalmol 16:530-532, 1977;.
Shin DH, Becker B:  The prognostic value of HLA-B12 and HLA-B7 antigens in patients with increased intraocular pressure . Am J Ophthalmol 82:871-874, 1976;.
Wilensky JT, Podos SM:  Prognostic parameters in primary open-angle glaucoma , in Symposium on Glaucoma: Transactions of the New Orleans Academy of Ophthalmology . St Louis, CV Mosby Co, 1975;, pp 7-30.
Havener W: Ocular Pharmacology , ed 3. St Louis, CV Mosby Co, 1974;, pp 214-223.
Duke-Elder S:  Diseases of the Lens and Vitreous: Glaucoma and Hypotony , vol 11, in Duke-Elder S (ed): System of Ophthalmology . St Louis, CV Mosby Co, 1969;, pp 516-518.

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