RT Journal
A1 Ratra D, Basia A
T1 INtravitreous tissue plasminogen activator with pneumatic displacement in submacular hemorrhage
JF Archives of Ophthalmology
JO Archives of Ophthalmology
YR 2012
FD June 1
VO 130
IS 6
SP 795
OP 796
DO 10.1001/archophthalmol.2011.1856
UL http://dx.doi.org/10.1001/archophthalmol.2011.1856
AB 
Submacular hemorrhage–induced retinal damage appears to vary directly with the duration of hemorrhage. Hence, many investigators have advocated early evacuation of subretinal hemorrhage to minimize these damaging effects. In 1996, Heriot1 presented the benefits of the minimally invasive procedure of enzymatically liquefying the submacular blood with tissue plasminogen activator (tPA) and displacing it with gas. Many studies have since shown good results with this procedure, but the exact time of the intervention is still debatable.2- 3 Although there is no consensus, submacular bleeding for more than 28 days is generally believed to give poor results.4 We report a case of submacular bleeding for 60 days that showed dramatic clearing within a day with tPA and gas.