RT Journal A1 Apple DJ, Wyhinny GJ, Goldberg MF, Bizzell JW, Broderson JP T1 Experimental argon laser photocoagulation: Iii. relative dangers of immediate vs delayed retreatment JF Archives of Ophthalmology JO Archives of Ophthalmology YR 1976 FD February 1 VO 94 IS 2 SP 309 OP 312 DO 10.1001/archopht.1976.03910030157015 UL http://dx.doi.org/10.1001/archopht.1976.03910030157015 AB • Monkey retinas were studied histopathologically to assess the relative effects of immediate versus delayed repetitive photocoagulation with the argon laser. Immediate retreatment adds relatively little damage to that created in the retinal nerve fiber layer by the initial photocoagulation. Delayed retreatment increases destruction of all retinal layers, including the nerve fiber layer, and also increases the chance of inducing hemorrhage. When argon laser retreatment of a retinal locus is necessary, it is much safer to do so immediately (within a few hours) rather than after days or weeks.