TY  - JOUR
T1  - CHronic myelogenous leukemia manifested as bilateral proliferative retinopathy
Y1  - 2005/04/01
N1  - 10.1001/archopht.123.4.576
JO  - Archives of Ophthalmology
SP  - 576
EP  - 576
VL  - 123
IS  - 4
N2  - 
A 27-year-old previously healthy man was seen with bilateral floaters, fatigue, and early satiety. His visual acuity was 20/80 OD and 20/70 OS. A clinical examination (Figure 1 and Figure 2) and fluorescein angiography (Figure 3) were performed. Laboratory analysis revealed a white blood cell count of 3.22 × 105/μL, with 12% bands, 14% metamyelocytes, 23% myelocytes, and 9% myeloblasts. Serum glucose and glycosylated hemoglobin levels were within normal limits. There was no evidence of hemoglobinopathy by electrophoresis. A bone marrow biopsy demonstrated the bcr-abl translocation (Figure 4). Chronic myelogenous leukemia was diagnosed, and the patient was given hydroxyurea, allopurinol, and imatinib mesylate (Gleevec). Ophthalmic treatment included panretinal photocoagulation and vitrectomy.

SN  - 0003-9950
M3  - doi: 10.1001/archopht.123.4.576
UR  - http://dx.doi.org/10.1001/archopht.123.4.576
ER  -