TY  - JOUR
T1  - PReliminary results of femtosecond laser–assisted descemet stripping endothelial keratoplasty
AU  - Cheng YY, Hendrikse F, Pels E, et al
Y1  - 2008/10/13
N1  - 10.1001/archopht.126.10.1351
JO  - Archives of Ophthalmology
SP  - 1351
EP  - 1356
VL  - 126
IS  - 10
N2  - Objective 
    To evaluate the preliminary visual results of femtosecond laser–assisted Descemet stripping endothelial keratoplasty (FS-DSEK).Methods 
    We prospectively analyzed results of 20 consecutive patients with Fuchs endothelial dystrophy or aphakic/pseudophakic bullous keratopathy who underwent FS-DSEK. Best spectacle-corrected visual acuity (BSCVA), refraction, corneal topography, and endothelial cell density were measured preoperatively and 3 and 6 months after FS-DSEK. Corneal thickness was measured using an optical coherence tomography technique.Results 
    The average BSCVA of 11 eyes with normal visual potential significantly improved from 20/110 ± 4 lines to 20/57 ± 1 line at 6 months (P < .007). At 6 months, the mean (SD) hyperopic shift was 2.24 (2.3) diopters (D). Preoperative and 6 months postoperative refractive astigmatism were −0.75 (0.9) D and −1.58 (1.1) D (P = .01), but the topographic astigmatism did not change postoperatively (P = .95). Mean (SD) endothelial cell density at 6 months was 1368 (425) cells/mm2. There was a persistent deswelling of the graft up to 3 months postoperatively. Complications included graft dislocations requiring repositioning (20%), pupillary block glaucoma (5%), epithelial ingrowth (5%), and primary graft failure (5%).Conclusions 
    Femtosecond laser–assisted Descemet stripping endothelial keratoplasty was effective in treating endothelial failure with minimal induced refractive astigmatism, limited improvement of BSCVA, and induction of a hyperopic shift. Endothelial cell count and dislocation rate were significant, which may be related to the surgical technique.
SN  - 0003-9950
M3  - doi: 10.1001/archopht.126.10.1351
UR  - http://dx.doi.org/10.1001/archopht.126.10.1351
ER  -