TY  - JOUR
T1  - CHanges in angioscotomas associated with the administration of sulfanilamide
AU  - ROSENTHAL CM
Y1  - 1939/07/01
N1  - 10.1001/archopht.1939.00860070089005
JO  - Archives of Ophthalmology
SP  - 73
EP  - 81
VL  - 22
IS  - 1
N2  - Widening of angioscotomas has been shown in cases of glaucoma, venous obstruction, retinal edema and raised intracranial pressure.1 In these cases the widening was believed to be due to a filling of the perivascular spaces with a relative or absolute damming back of the fluid to the synapses of the first and second neurons of the retina.2It has been shown by Evans and McFarland3 that angioscotomas also widened when the person under study was subjected to oxygen deprivation. The recently reported effect of sulfanilamide on trachomatous pannus and the known relation of sulfanilamide to the oxygen-carrying substance of the blood and hemoglobin seemed to indicate that a study of the relation of sulfanilamide to angioscotomas might be fruitful. With this thought in mind it became necessary to review certain aspects of the knowledge of sulfanilamide.Sulfanilamide, chemically, is an azo compound, paraaminobenzenesulfonamide. It is interesting to
SN  - 0093-0326
M3  - doi: 10.1001/archopht.1939.00860070089005
UR  - http://dx.doi.org/10.1001/archopht.1939.00860070089005
ER  -