TY  - JOUR
T1  - CAlcification of bruch's membrane in angioid streaks with homozygous sickle cell disease
AU  - Jampol LM, Acheson R, Eagle RC, Jr, Serjeant G, O'Grady R
Y1  - 1987/01/01
N1  - 10.1001/archopht.1987.01060010099039
JO  - Archives of Ophthalmology
SP  - 93
EP  - 98
VL  - 105
IS  - 1
N2  - • Histochemical and light and electron microscopic studies of two eyes of a patient with homozygous sickle cell disease and angioid streaks demonstrated heavy calcification and breaks in Bruch's membrane. We were unable to demonstrate iron deposition by histochemical techniques or transmission electron microscopy. These studies suggest that calcification rather than iron deposition is the major factor leading to brittleness of Bruch's membrane in patients with hemolytic anemia and angioid streaks.
SN  - 0003-9950
M3  - doi: 10.1001/archopht.1987.01060010099039
UR  - http://dx.doi.org/10.1001/archopht.1987.01060010099039
ER  -