TY  - JOUR
T1  - EXposure to sunlight and other risk factors for age-related macular degeneration
AU  - West SK, Rosenthal FS, Bressler NM, et al
Y1  - 1989/06/01
N1  - 10.1001/archopht.1989.01070010897038
JO  - Archives of Ophthalmology
SP  - 875
EP  - 879
VL  - 107
IS  - 6
N2  - • As some ultraviolet (UV) radiation is transmitted by the ocular media, there is a growing concern that there may be a possible relationship between long-term exposure to ultraviolet radiation and increased risk of age-related macular degeneration. To address this question, a survey was conducted of 838 Maryland watermen who had well-characterized ocular UV-A and UV-B exposure. Fundus photographs were taken and graded for presence of exudative disease, geographic atrophy, focal hyperpigmentation of the retinal pigment epithelium, and drusen that were large and/or confluent. None of the subjects in these analyses were aphakic. The results suggested that age-related macular degeneration was not associated with cumulative exposure to either UV-A or UV-B. Age and the presence of nuclear opacity were independently associated with an increased risk of macular degeneration. Thus, we found that in phakic subjects, even with high levels of sunlight exposure, there was no evidence of increased risk of age-related macular degeneration associated with UV-B or UV-A exposure.
SN  - 0003-9950
M3  - doi: 10.1001/archopht.1989.01070010897038
UR  - http://dx.doi.org/10.1001/archopht.1989.01070010897038
ER  -