TY - JOUR T1 - THe increased risk of ulcerative keratitis among disposable soft contact lens users AU - Buehler PO, Schein OD, Stamler JF, Verdier DD, Katz J Y1 - 1992/11/01 N1 - 10.1001/archopht.1992.01080230055019 JO - Archives of Ophthalmology SP - 1555 EP - 1558 VL - 110 IS - 11 N2 - • Previous controlled studies on contact lens-associated ulcerative keratitis were performed before the widespread use of disposable contact lenses. Therefore, a controlled study was undertaken to determine the relative risk of ulcerative keratitis among users of disposable soft contact lenses compared with the risk among users of other lens types. Forty-six consecutive cases of contact lens-associated ulcerative keratitis were identified between January 1990 and June 1992 at a corneal specialty practice in western Michigan. Five controls, matched to each case patient according to the dispensing date and prescribing practitioner, were obtained for 42 cases (91%). Users of dailywear rigid gas-permeable lenses had the lowest risk of developing ulcerative keratitis. Relative to users of daily-wear soft contact lenses, users of extended-wear soft contact lens had an age-adjusted and sex-adjusted relative risk of 1.87 (95% confidence interval, 0.61 to 5.71). Disposable soft contact lens users had the highest risk of developing ulcerative keratitis, with an adjusted relative risk of 14.16 (95% confidence interval, 5.47 to 37.63) compared with daily-wear soft contact lens users and 7.66 (95% confidence interval, 2.27 to 25.83) compared with conventional extended-wear soft contact lens users. SN - 0003-9950 M3 - doi: 10.1001/archopht.1992.01080230055019 UR - http://dx.doi.org/10.1001/archopht.1992.01080230055019 ER -