TY  - JOUR
T1  - REduced trabecular meshwork height in juvenile primary open-angle glaucoma
AU  - Stegman Z, Sokol J, Liebmann JM, Cohen H, Tello C, Ritch R
Y1  - 1996/06/01
N1  - 10.1001/archopht.1996.01100130652003
JO  - Archives of Ophthalmology
SP  - 660
EP  - 663
VL  - 114
IS  - 6
N2  - Objective: 
    To compare trabecular meshwork height in a series of patients with juvenile primary open-angle glaucoma (JPOAG) with that in normal control patients.Methods: 
    Ultrasound biomicroscopy and A-scan biometry were performed on 16 eyes with JPOAG and 24 normal eyes. A radial, perpendicular image in the horizontal temporal meridian detailing the line of Schwalbe, scleral spur, and angle anatomy was obtained for each eye by a single examiner. Trabecular meshwork height was defined as the distance from the scleral spur to the Schwalbe line.Results: 
    Mean patient age (P=.85, t test), refractive error (P=.68), sex distribution (P=.26, Fisher exact test) and axial length (P=.39) were similar between the groups. Mean±SE trabecular meshwork heights were 0.36±0.03 mm (range, 0.19-0.53 mm) for JPOAG and 0.58±0.02 mm (range, 0.40-0.80 mm) for controls (P<.001). Eyes with greater axial length tended to have larger trabecular meshworks in both groups (P=.012, multivariate regression). A trabecular meshwork height-axial length ratio of 0.021 or less was associated with a significantly increased risk for JPOAG being present (odds ratio, 57; 95% confidence interval, 6.0-541).Conclusion: 
    The trabecular meshwork is smaller in eyes with JPOAG compared with that in normal eyes. This finding suggests a structural abnormality that may underlie the reduced outflow.
SN  - 0003-9950
M3  - doi: 10.1001/archopht.1996.01100130652003
UR  - http://dx.doi.org/10.1001/archopht.1996.01100130652003
ER  -