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Basic View | Expanded View
 Showing 1-20 of 67 Articles
Viewpoint 
Farzin Forooghian, MD, MSc, FRCSC
This Viewpoint discusses the importance of standardization in serum antiretinal antibody testing for diagnosing autoimmune retinopathy.
Original Investigation 
Aaron Fay, MD; Nambi Nallasamy, MD; Francesco Bernardini, MD; Edward J. Wladis, MD; Marlene L. Durand, MD; Martin H. Devoto, MD; Dale Meyer, MD; Morris Hartstein, MD; Santosh Honavar, MD; Midori H. Osaki, MD; Tammy H. Osaki, MD; Yvette M. Santiago, MD; Marco Sales-Sanz, MD, PhD; Giuseppe Vadala, MD; David Verity, MD

Importance  Antibiotic stewardship is important in controlling resistance, adverse reactions, and cost. The literature regarding antibiotic use for eyelid surgery is lacking.

Objectives  To determine standard care and assess factors influencing antibiotic prescribing practices for eyelid surgery.

Design, Setting, and Participants  A survey study was ...

Original Investigation 
Anne Marie Lane, MPH; Ivana K. Kim, MD; Evangelos S. Gragoudas, MD

Importance  Little is known about the long-term risk of dying of uveal melanoma after treatment with radiotherapy.

Objective  To determine the long-term risk of dying of this disease, we evaluated melanoma-related mortality rates up to 25 years after proton beam therapy in a large series of ...

Brief Report 
Ashvini K. Reddy, MD; Marco A. Gonzalez, MD; Christopher R. Henry, MD; Steven Yeh, MD; Lucia Sobrin, MD; Thomas A. Albini, MD

Importance  To describe a cohort of patients with birdshot chorioretinopathy who did not manifest birdshot lesions on clinical examination but had retinal vasculitis, low-grade to moderate vitritis, and hypocyanescent lesions on indocyanine green angiography (ICGA).

Observations  Case series of 3 patients with mild to moderate vitritis ...

Observation 
Prethy Rao, MD, MPH; Benjamin J. Thomas, MD; Yoshihiro Yonekawa, MD; Joshua Robinson, MD; Antonio Capone Jr, MD
Wyburn-Mason syndrome is a unilateral, sporadic disorder characterized by arteriovenous malformations (AVMs) of the retina, face, and central nervous system. Clinically, these lesions often manifest as dilated, tortuous retinal vessels.1 We report a complication of Wyburn-Mason syndrome, peripheral retinal neovascularization, that has not yet been described to our knowledge. Additionally, ...
To the Editor An additional comment on the cost-analysis model comparing immediate sequential cataract surgery (ISCS) with delayed sequential cataract surgery (DSCS) in the United States from the societal and physician perspectives would be beneficial.1,2 Physicians were shown to have a decline in physician practice–derived income with a conversion to ...
Viewpoint 
Christine Shieh, MD; Gargi Vora, MD; Terry Kim, MD
This Viewpoint reports on Ebola virus disease and the current Ebola epidemic, which has been deemed the largest in history.
Editorial 
Michael V. Boland, MD, PhD
The Health Information Technology for Economic and Clinical Health Act adopted in 2009 was designed to increase the use of electronic health records (EHRs) by US health care professionals and hospitals via a system of incentive payments. As of December 2014, almost 340 000 professionals received these payments via Medicare ...
Original Investigation 
Rishi P. Singh, MD; Rumneek Bedi, BS; Ang Li, BS; Sharmila Kulkarni, BS; Tiffany Rodstrom, COT, RN; Gene Altus, BA, MBA; Daniel F. Martin, MD
Includes: Supplemental Content

Importance  Given the lack of previous reports examining the impact of electronic health record (EHR) system migration in ophthalmology, a study evaluating the practice and economic effect of implementing an EHR into an ophthalmic practice is warranted.

Objective  To examine the clinical and economic impact of ...

Editorial: Electronic Health Records and Ophthalmology; Michael V. Boland, MD, PhD
Original Investigation 
Hidenobu Tanihara, MD; Toshihiro Inoue, MD; Tetsuya Yamamoto, MD; Yasuaki Kuwayama, MD; Haruki Abe, MD; Hideki Suganami, PhD; Makoto Araie, MD; for the K-115 Clinical Study Group
Includes: Supplemental Content

Importance  Ripasudil hydrochloride hydrate (K-115), a novel rho kinase inhibitor, provides statistically significant intraocular pressure (IOP)–lowering effects and has a tolerable safety profile. However, no studies have evaluated ripasudil combined with β-blockers and prostaglandin analogues.

Objective  To evaluate the additive IOP-lowering effects and the safety of ...

Original Investigation 
James T. Rosenbaum, MD; Dongseok Choi, PhD; David J. Wilson, MD; Hans E. Grossniklaus, MD; Christina A. Harrington, PhD; Cailin H. Sibley, MD; Roger A. Dailey, MD; John D. Ng, MD; Eric A. Steele, MD; Craig N. Czyz, MD; Jill A. Foster, MD; David Tse, MD; Chris Alabiad, MD; Sander Dubovy, MD; Prashant Parekh, MD; Gerald J. Harris, MD; Michael Kazim, MD; Payal Patel, MD; Valerie White, MD; Peter Dolman, MD; Bobby S. Korn, MD; Don Kikkawa, MD; Deepak P. Edward, MD; Hind Alkatan, MD; Hailah al-Hussain, MD; R. Patrick Yeatts, MD; Dinesh Selva, MBBS, FRANZCO, FRACS; Patrick Stauffer, BA; Stephen R. Planck, PhD
Includes: Supplemental Content

Importance  Sarcoidosis is a major cause of ocular or periocular inflammation. The pathogenesis of sarcoidosis is incompletely understood and diagnosis often requires a biopsy.

Objective  To determine how gene expression in either orbital adipose tissue or the lacrimal gland affected by sarcoidosis compares with gene expression ...

Original Investigation 
Daniela Ferrara, MD, PhD; Johanna M. Seddon, MD, ScM
Includes: Supplemental Content

Importance  The complement factor H R1210C rare variant confers the strongest genetic risk for age-related macular degeneration and earlier age at onset; however, its associated phenotype has not been well characterized.

Objective  To describe specific fundus features of a white population with the R1210C rare variant....

Observation 
Jessica R. Chang, MD; Michael P. Grant, MD, PhD; Shannath L. Merbs, MD, PhD
Functional endoscopic sinus surgery (FESS) is a commonly performed procedure that has a risk of serious ophthalmic complications. We report a case of complete enucleation as a complication of FESS.
Viewpoint 
Aaron Nagiel, MD, PhD; SriniVas R. Sadda, MD; David Sarraf, MD
This Viewpoint reports on optical coherence tomography angiography and how its use could greatly enrich our understanding of the ischemic processes affecting different layers of the retinal vasculature.
Original Investigation 
Caitlin L. M. Kakigi, BA; Kuldev Singh, MD, MPH; Sophia Y. Wang, MD; Wayne T. Enanoria, PhD, MPH; Shan C. Lin, MD
Includes: Supplemental Content

Importance  Despite widespread use of calcium supplementation among elderly people, little is known about the association between such consumption and the prevalence of age-related macular degeneration (AMD) in the United States.

Objective  To investigate the association between self-reported supplementary calcium consumption and the prevalence of AMD ...

Original Investigation 
Judith E. Goldstein, OD; Mary Lou Jackson, MD; Sandra M. Fox, OD; James T. Deremeik, CLVT; Robert W. Massof, PhD; for the Low Vision Research Network Study Group

Importance  To facilitate comparative clinical outcome research in low vision rehabilitation, we must use patient-centered measurements that reflect clinically meaningful changes in visual ability.

Objective  To quantify the effects of currently provided low vision rehabilitation (LVR) on patients who present for outpatient LVR services in the ...

Observation 
Stéphanie Hayek, MD; Antoine Rousseau, MD; Elise Bouthry, MD; Christine M. Prat, PhD; Marc Labetoulle, MD, PhD
Chikungunya virus (CHIKV) is a mosquito-borne viral disease caused by an arbovirus from the Togaviridae family. It is endemic in parts of Africa and Southeast Asia and on the Indian subcontinent.1 In December 2013, autochthonous chikungunya cases were confirmed on Saint-Martin island in the French West Indies. This was the ...
Original Investigation 
Karla Zadnik, OD, PhD; Loraine T. Sinnott, PhD; Susan A. Cotter, OD, MS; Lisa A. Jones-Jordan, PhD; Robert N. Kleinstein, OD, MPH, PhD; Ruth E. Manny, OD, PhD; J. Daniel Twelker, OD, PhD; Donald O. Mutti, OD, PhD; for the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study Group

Importance  Myopia (nearsightedness) has its onset in childhood and affects about one-third of adults in the United States. Along with its high prevalence, myopia is expensive to correct and is associated with ocular diseases that include glaucoma and retinal detachment.

Objective  To determine the best set ...

Original Investigation 
Nichole D. L. Joachim, BSc(Hons); Paul Mitchell, MD, PhD; Annette Kifley, MAppStats, PhD; Jie Jin Wang, MMed, PhD

Importance  The natural course and prognosis of medium drusen and risk factors associated with the incidence and progression of this lesion type in age-related macular degeneration (AMD) are not well understood.

Objective  To assess the 15-year incidence and progression of medium drusen and associated risk factors....

Importance  Retinal hemorrhages are an important sequela of fatal head trauma. The accurate pathologic diagnosis of retinal hemorrhages has critical implications for determination of the manner of death.

Observations  We describe an autolytic postmortem histologic artifact of eosinophilic Müller cell foot process swelling that mimics a ...

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