http://archopht.jamanetwork.com/ en-us Thu, 02 May 2013 00:00:00 GMT Thu, 02 May 2013 16:47:47 GMT Silverchair editor@archopht.jamanetwork.com webmaster@archopht.jamanetwork.com http://archopht.jamanetwork.com/article.aspx?articleID=1682371 Thu, 02 May 2013 00:00:00 GMT Char DH, Cole TB, Crawford J. <span class="paragraphSection">As many as 20% of uveal melanoma–containing eyes historically had opaque media and more than half of such tumors were unsuspected. While many ophthalmic oncologic centers, including ours, have more than 99% accuracy of uveal melanoma diagnosis, in eyes with opaque media and extensive necrosis the correct diagnosis can sometimes be impossible to establish with ultrasonography, magnetic resonance imaging (MRI), and fine-needle aspiration biopsy (FNAB). We present 5 cases that illustrate these problems.</span> 1 3 10.1001/jamaophthalmol.2013.231 http://archopht.jamanetwork.com/article.aspx?articleID=1682371